Nutrition and Food Security Research Centre, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Nutr Diet. 2019 Sep;76(4):462-471. doi: 10.1111/1747-0080.12463. Epub 2018 Aug 15.
To examine the relationship between dietary patterns and inflammatory markers including serum high sensitivity C-reactive protein (hs-CRP) and interleukin 17A (IL-17A) in females.
In the present cross-sectional study in female teachers living in Yazd, central Iran, data on anthropometric measurements and general information were gathered. A food frequency questionnaire was completed by participants and then, subjects were invited to give blood samples. Major dietary patterns were derived using principal component analysis and serum inflammatory markers were compared according to quintiles of dietary patterns scores.
In total, 320 subjects aged 40.38 ± 8.08 years were included. Three dietary patterns were derived: (i) 'traditional' with a high intake of poultry, salt, eggs, other vegetables and red meat; (ii) 'vegetables and fruits' with a higher intake of tomatoes, yoghurt drinks, green leafy vegetables, dried fruits, fruits, other vegetables and organ meats and (iii) 'dairy and saturated fat' with a high loading of high-fat dairy products, butter, low-fat dairy, margarine, eggs, other vegetables and green leafy vegetables. Participants in the highest quintile of the 'vegetables and fruits' dietary pattern had significantly lower serum hs-CRP levels compared to those in the lowest quintile (3.6 ± 0.4 mg/L vs 2.6 ± 0.4 mg/L, respectively; P < 0.05). None of the dietary patterns were associated with circulating IL-17 levels.
Higher consumption of fruits and vegetables is inversely associated with serum hs-CRP but not IL-17 levels. Studies investigating the dietary patterns in association with IL-17 in other populations are recommended.
探讨女性饮食模式与炎症标志物（包括血清高敏 C 反应蛋白（hs-CRP）和白细胞介素 17A（IL-17A））之间的关系。
本研究为伊朗中部亚兹德女性教师的横断面研究，收集了参与者的人体测量学数据和一般信息。参与者完成了食物频率问卷，随后邀请他们抽血。采用主成分分析法提取主要饮食模式，并根据饮食模式评分的五分位数比较血清炎症标志物。
共纳入 320 名年龄 40.38±8.08 岁的女性。提取出 3 种饮食模式：（i）“传统”模式，禽类、盐、鸡蛋、其他蔬菜和红肉摄入量较高；（ii）“蔬菜和水果”模式，西红柿、酸奶饮料、绿叶蔬菜、干果、水果、其他蔬菜和动物内脏摄入量较高；（iii）“奶制品和饱和脂肪”模式，高脂肪乳制品、黄油、低脂乳制品、人造黄油、鸡蛋、其他蔬菜和绿叶蔬菜的摄入量较高。“蔬菜和水果”饮食模式五分位最高组的血清 hs-CRP 水平明显低于五分位最低组（分别为 3.6±0.4mg/L 和 2.6±0.4mg/L，P<0.05）。没有一种饮食模式与循环 IL-17 水平相关。
更多地摄入水果和蔬菜与血清 hs-CRP 呈负相关，而与 IL-17 水平无关。建议开展其他人群中与 IL-17 相关的饮食模式研究。
