Oke S M, Segal J, Clark S K, Hart A L, Gabe S M
St. Mark's Hospital , Harrow , UK.
Department of Surgery and Cancer, Imperial College , London , UK.
Ann R Coll Surg Engl. 2019 Jan;101(1):17-20. doi: 10.1308/rcsann.2018.0131. Epub 2018 Aug 16.
Restorative proctocolectomy is a surgical treatment for patients with medically refractory ulcerative colitis and some cases of familial adenomatous polyposis. Intestinal failure, defined as an inability to maintain adequate hydration and micronutrient balances when on a conventionally accepted normal diet, is a rare complication of restorative proctocolectomy. We describe our experience of patients with restorative proctocolectomy who have developed intestinal failure requiring parenteral support.
This was a retrospective analysis using a database of patients referred to our intestinal failure unit from January 1998 to January 2016. We analysed the records of all those patients who had restorative proctocolectomy who developed intestinal failure.
807 patient records analysed, 35 patients were found to have had a restorative proctocolectomy (13 male and 22 female). Ninety-one percent (n = 32) of patients developed IF as a consequence of unpredictable complications which occurred after RPC formation. Potentially predictable complications were noted in 9% (n = 3) of patients.
Most cases of intestinal failure in restorative proctocolectomy were unpredictable. In a small number of patients, accurate assessment and measurement of the small intestine may have better predicted the adverse outcome of intestinal failure allowing improved pre-operative counseling of patients.
保留直肠的结肠切除术是治疗药物难治性溃疡性结肠炎患者以及某些家族性腺瘤性息肉病患者的一种手术方式。肠衰竭被定义为在接受传统公认的正常饮食时无法维持充足的水合作用和微量营养素平衡,是保留直肠的结肠切除术罕见的并发症。我们描述了接受保留直肠的结肠切除术且出现需要肠外支持的肠衰竭患者的情况。
这是一项回顾性分析,使用了1998年1月至2016年1月转诊至我们肠衰竭治疗中心的患者数据库。我们分析了所有接受保留直肠的结肠切除术并出现肠衰竭的患者的记录。
分析了807份患者记录,发现35例患者接受了保留直肠的结肠切除术(13例男性和22例女性)。91%(n = 32)的患者因保留直肠的结肠切除术形成后出现的不可预测并发症而发生肠衰竭。9%(n = 3)的患者出现了潜在可预测的并发症。
保留直肠的结肠切除术中多数肠衰竭病例是不可预测的。在少数患者中,对小肠进行准确评估和测量可能能更好地预测肠衰竭的不良结局,从而改善对患者的术前咨询。