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脑瘫患者髋关节半脱位软组织松解手术成功的术前放射学预测因素:一项符合STROBE标准的研究

Preoperative radiologic predictors of successful soft tissue release surgery for hip subluxation among cerebral palsy patients: A STROBE compliant study.

作者信息

Ha Myongsu, Okamoto Takashi, Fukuta Toshitsugu, Tsuboi Yoshiaki, Shirai Yasuhiro, Hattori Kazuki, Sakuma Eisuke, Wakabayashi Kenjiro, Wada Ikuo, Otsuka Takanobu

机构信息

Department of Orthopedic Surgery Department of Molecular and Cellular Biology Department of Integrative Anatomy Department of Rehabilitation Medicine, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

出版信息

Medicine (Baltimore). 2018 Aug;97(33):e11847. doi: 10.1097/MD.0000000000011847.

Abstract

Paralytic hip subluxation is a common problem in children with cerebral palsy. Although surgical procedures such as soft tissue release and osteotomy have been advocated for its prevention, the exact indications of such procedures remain unclear. We attempted to evaluate preoperative radiographic parameters and identify prognostic factors in children with cerebral palsy. We retrospectively investigated 43 hips in 27 children with cerebral palsy who had undergone soft tissue release surgery for hip subluxation. We evaluated the age at the time of surgery and the radiographic parameters such as the center-edge angle (CEA), the migration percentage (MP), and the acetabular index (AI) at 3 time points: preoperation, 1 year after surgery, and at final follow-up. The outcome measure was determined by the MP value at final follow-up. Student t test was used to compare the quantitative variables between 2 groups (good vs poor outcome). Then the multiple regression analysis was applied to determine the prognostic factors upon soft tissue release surgery. Children with good outcome exhibited higher CEA (average value of -1.43° vs -13.2° in those with poor outcome), lower MP (53.9% vs 71.3%), and lower AI (28.1° vs 35.3°). Upon multiple regression analysis, we found that the age at the time of surgery, preoperative CEA, and preoperative MP did not appear to be independent prognostic factors. The only independent factor that affected prognosis after soft tissue release surgery was the preoperative AI. The preoperative AI values <34° were associated with the good outcome with specificity of 87% and sensitivity of 60% according to the receiver operating characteristic curve analysis. These findings indicate that the outcome of soft tissue release surgery can be predicted by the preoperative AI value.

摘要

麻痹性髋关节半脱位是脑瘫患儿的常见问题。尽管软组织松解和截骨术等外科手术已被提倡用于预防该问题,但其确切指征仍不明确。我们试图评估脑瘫患儿的术前影像学参数并确定预后因素。我们回顾性研究了27例因髋关节半脱位接受软组织松解手术的脑瘫患儿的43个髋关节。我们评估了手术时的年龄以及3个时间点的影像学参数,即中心边缘角(CEA)、移位百分比(MP)和髋臼指数(AI):术前、术后1年和最终随访时。结局指标由最终随访时的MP值确定。采用学生t检验比较两组(预后良好与预后不良)之间的定量变量。然后应用多元回归分析确定软组织松解手术后的预后因素。预后良好的患儿表现出更高的CEA(平均-1.43°,而预后不良者为-13.2°)、更低的MP(53.9%对71.3%)和更低的AI(28.1°对35.3°)。经多元回归分析,我们发现手术时的年龄、术前CEA和术前MP似乎不是独立的预后因素。软组织松解手术后影响预后的唯一独立因素是术前AI。根据受试者工作特征曲线分析,术前AI值<34°与良好预后相关,特异性为87%,敏感性为60%。这些发现表明软组织松解手术的结局可通过术前AI值预测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7a7/6112945/ab7155d33754/medi-97-e11847-g002.jpg

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