• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Atopic diseases/diathesis and subsequent ischemic stroke among patients with bipolar disorder: A nationwide longitudinal study.特应性疾病/素质与双相障碍患者随后发生的缺血性卒中：一项全国性纵向研究。
PLoS One. 2018 Aug 16;13(8):e0200682. doi: 10.1371/journal.pone.0200682. eCollection 2018.
2
Risk of developing major depression and bipolar disorder among adolescents with atopic diseases: A nationwide longitudinal study in Taiwan.患有特应性疾病的青少年患重度抑郁症和双相情感障碍的风险：台湾一项全国性纵向研究
J Affect Disord. 2016 Oct;203:221-226. doi: 10.1016/j.jad.2016.06.012. Epub 2016 Jun 7.
3
Atopic Diseases and Subsequent Ischemic Stroke Among Patients With Schizophrenia: A Nationwide Longitudinal Study.精神分裂症患者的特应性疾病与随后的缺血性卒中：一项全国性纵向研究。
Psychosom Med. 2015 Nov-Dec;77(9):1031-8. doi: 10.1097/PSY.0000000000000234.
4
Atopic dermatitis and risk of ischemic stroke: a nationwide population-based study.特应性皮炎与缺血性脑卒中风险：一项全国范围内基于人群的研究。
Ann Med. 2014 Mar;46(2):84-9. doi: 10.3109/07853890.2013.870018. Epub 2014 Jan 27.
5
Risk of developing major depressive disorder and anxiety disorders among adolescents and adults with atopic dermatitis: a nationwide longitudinal study.特应性皮炎青少年和成年人中发生重度抑郁症和焦虑症的风险：一项全国性纵向研究。
J Affect Disord. 2015 Jun 1;178:60-5. doi: 10.1016/j.jad.2015.02.025. Epub 2015 Mar 5.
6
A predisposition for allergies predicts subsequent hypertension, dyslipidemia, and diabetes mellitus among patients with schizophrenia or bipolar disorder: a nationwide longitudinal study.过敏易感性预示着精神分裂症或双相情感障碍患者随后会出现高血压、血脂异常和糖尿病：一项全国性纵向研究。
Schizophr Res. 2014 Oct;159(1):171-5. doi: 10.1016/j.schres.2014.07.029. Epub 2014 Aug 10.
7
Nonapnea sleep disorders are associated with subsequent ischemic stroke risk: a nationwide, population-based, retrospective cohort study.非呼吸暂停性睡眠障碍与随后的缺血性卒中风险相关：一项全国性、基于人群的回顾性队列研究。
Sleep Med. 2013 Dec;14(12):1341-7. doi: 10.1016/j.sleep.2013.07.017. Epub 2013 Oct 16.
8
Risk of epilepsy among patients with atopic dermatitis: a nationwide longitudinal study.特应性皮炎患者的癫痫风险：一项全国性纵向研究。
Epilepsia. 2014 Aug;55(8):1307-12. doi: 10.1111/epi.12667. Epub 2014 Jun 10.
9
Is atopy in early childhood a risk factor for ADHD and ASD? a longitudinal study.婴幼儿时期的特应性是否是 ADHD 和 ASD 的危险因素？一项纵向研究。
J Psychosom Res. 2014 Oct;77(4):316-21. doi: 10.1016/j.jpsychores.2014.06.006. Epub 2014 Jun 21.
10
Chronic rhinosinusitis increases the risk of hemorrhagic and ischemic stroke: A longitudinal follow-up study using a national sample cohort.慢性鼻-鼻窦炎增加出血性和缺血性卒中风险：基于全国样本队列的纵向随访研究。
PLoS One. 2018 Mar 1;13(3):e0193886. doi: 10.1371/journal.pone.0193886. eCollection 2018.

引用本文的文献

1
Mapping review of register-based cohort studies of bipolar disorder.基于登记册的双相情感障碍队列研究的映射综述
Bipolar Disord. 2024 Dec;26(8):764-771. doi: 10.1111/bdi.13491. Epub 2024 Aug 26.
2
High Risk Factors and Preventive Measures of Bipolar Disorder After Ischemic Stroke.缺血性卒中后双相情感障碍的高危因素及预防措施
Alpha Psychiatry. 2024 Mar 1;25(2):220-225. doi: 10.5152/alphapsychiatry.2024.231467. eCollection 2024 Mar.
3
Correlation between the levels of NLRP3, Hcy, IL-1β, IL-18 and the prognosis in patients with hemorrhagic stroke.出血性脑卒中患者NLRP3、同型半胱氨酸、白细胞介素-1β、白细胞介素-18水平与预后的相关性
Am J Transl Res. 2021 Apr 15;13(4):2883-2890. eCollection 2021.

本文引用的文献

1
Cognition-Modulated Frontal Activity in Prediction and Augmentation of Antidepressant Efficacy: A Randomized Controlled Pilot Study.认知调节的额叶活动在预测和增强抗抑郁疗效中的作用：一项随机对照试验性研究
Cereb Cortex. 2016 Jan;26(1):202-10. doi: 10.1093/cercor/bhu191. Epub 2014 Aug 27.
2
A predisposition for allergies predicts subsequent hypertension, dyslipidemia, and diabetes mellitus among patients with schizophrenia or bipolar disorder: a nationwide longitudinal study.过敏易感性预示着精神分裂症或双相情感障碍患者随后会出现高血压、血脂异常和糖尿病：一项全国性纵向研究。
Schizophr Res. 2014 Oct;159(1):171-5. doi: 10.1016/j.schres.2014.07.029. Epub 2014 Aug 10.
3
Risk of dementia among patients with asthma: a nationwide longitudinal study.哮喘患者痴呆风险：一项全国性纵向研究。
J Am Med Dir Assoc. 2014 Oct;15(10):763-7. doi: 10.1016/j.jamda.2014.06.003. Epub 2014 Jul 15.
4
The association of atopy with incidence of ischemic heart disease, stroke, and diabetes.特应性与缺血性心脏病、中风和糖尿病发病率的关联。
Endocrine. 2015 Mar;48(2):541-50. doi: 10.1007/s12020-014-0321-z. Epub 2014 Jun 12.
5
Risk of myocardial infarction and stroke in bipolar disorder: a systematic review and exploratory meta-analysis.双相情感障碍患者发生心肌梗死和中风的风险：一项系统评价与探索性Meta分析
Acta Psychiatr Scand. 2014 Nov;130(5):342-53. doi: 10.1111/acps.12293. Epub 2014 May 22.
6
Cytokines in bipolar disorder: recent findings, deleterious effects but promise for future therapeutics.双相情感障碍中的细胞因子：近期研究发现、有害影响及未来治疗前景
CNS Spectr. 2011 Jul;16(7):157-68. doi: 10.1017/S1092852912000338.
7
Association of IL-6-174G > C and -572C > G polymorphisms with risk of young ischemic stroke patients.白细胞介素 6-174G>C 和-572C>G 多态性与青年缺血性脑卒中患者发病风险的相关性。
Gene. 2014 Apr 15;539(2):258-62. doi: 10.1016/j.gene.2014.01.054. Epub 2014 Jan 29.
8
Atopic dermatitis and risk of ischemic stroke: a nationwide population-based study.特应性皮炎与缺血性脑卒中风险：一项全国范围内基于人群的研究。
Ann Med. 2014 Mar;46(2):84-9. doi: 10.3109/07853890.2013.870018. Epub 2014 Jan 27.
9
Metabolic syndrome and asthma.代谢综合征与哮喘。
Recent Pat Endocr Metab Immune Drug Discov. 2014 Jan;8(1):60-6. doi: 10.2174/1872214807666140107151023.
10
Chronic disease co-morbidity of asthma and unscheduled asthma care among adults: results of the national telephone health interview survey German Health Update (GEDA) 2009 and 2010.成人哮喘的慢性病共病情况及非计划哮喘护理：2009年和2010年德国健康更新全国电话健康访谈调查结果
Prim Care Respir J. 2014 Mar;23(1):22-9. doi: 10.4104/pcrj.2013.00107.

特应性疾病/素质与双相障碍患者随后发生的缺血性卒中：一项全国性纵向研究。

Atopic diseases/diathesis and subsequent ischemic stroke among patients with bipolar disorder: A nationwide longitudinal study.

机构信息

Department of Psychiatry, Taipei Veterans General Hospital, Taipei, Taiwan.

Department of Psychiatry, Cheng Hsin General Hospital, Taipei, Taiwan.

出版信息

PLoS One. 2018 Aug 16;13(8):e0200682. doi: 10.1371/journal.pone.0200682. eCollection 2018.

DOI:10.1371/journal.pone.0200682
PMID:30114239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6095510/
Abstract

INTRODUCTION

Previous studies have suggested that both bipolar disorder and atopy are associated with an increased risk of stroke. However, the role of atopic diseases/diathesis in the risk of stroke among patients with bipolar disorder remains unclear.

METHODS

Using Taiwan's National Health Insurance Research Database, we selected 55,593 patients with bipolar disorder between 2002 and 2008, divided them into patients with atopic diseases/diathesis (n = 21,050) and patients without atopic diseases/diathesis (n = 34,543), and observed them until the end of 2011. Patients who experienced a stroke during the follow-up period were identified.

RESULTS

Patients with bipolar disorder and atopic diseases/diathesis had an elevated risk of ischemic stroke (hazard ratio [HR]: 1.44, 95% confidence interval [CI]: 1.25-1.59) compared with patients with only bipolar disorder; a dose-dependent relationship was observed between the number of allergic comorbidities and the risk of ischemic stroke (1 atopic disease, HR: 1.30, 95% CI: 1.13-1.49; 2 atopic diseases, HR: 1.59, 95% CI: 1.33-1.91; ≥ 3 atopic diseases, HR: 2.09, 95% CI: 1.50-2.91).The role of atopic diseases in the risk of hemorrhagic stroke among patients with bipolar disorder was nonsignificant (HR: 0.84, 95% CI: 0.64-1.09).

CONCLUSIONS

Patients with bipolar disorder and atopic diseases/diathesis are more prone to ischemic stroke later in life than are those without atopic diseases/diathesis. Further study is required to investigate the underlying mechanism linking atopy, bipolar disorder, and stroke.

摘要

简介

先前的研究表明，双相情感障碍和特应性都与中风风险增加有关。然而，特应性疾病/体质在双相情感障碍患者中风风险中的作用尚不清楚。

方法

我们使用台湾全民健康保险研究数据库，选取了 2002 年至 2008 年间 55593 名双相情感障碍患者，将他们分为有特应性疾病/体质（n=21050）和无特应性疾病/体质（n=34543）两组，并观察他们至 2011 年底。在随访期间发生中风的患者被识别出来。

结果

与仅有双相情感障碍的患者相比，患有双相情感障碍和特应性疾病/体质的患者发生缺血性中风的风险升高（风险比[HR]：1.44，95%置信区间[CI]：1.25-1.59）；过敏合并症的数量与缺血性中风的风险之间存在剂量依赖性关系（1 种特应性疾病，HR：1.30，95%CI：1.13-1.49；2 种特应性疾病，HR：1.59，95%CI：1.33-1.91；≥3 种特应性疾病，HR：2.09，95%CI：1.50-2.91）。特应性疾病在双相情感障碍患者发生出血性中风风险中的作用不显著（HR：0.84，95%CI：0.64-1.09）。

结论

患有双相情感障碍和特应性疾病/体质的患者比没有特应性疾病/体质的患者在以后的生活中更容易发生缺血性中风。需要进一步研究以探讨特应性、双相情感障碍和中风之间的潜在机制。