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利用工程微生物生产应用于食品工业的植物代谢物。

Production of plant metabolites with applications in the food industry using engineered microorganisms.

机构信息

Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, D-52425 Jülich, Germany.

Institute of Bio- and Geosciences, IBG-1: Bioorganic Chemistry, D-52425 Jülich, Germany.

出版信息

Curr Opin Biotechnol. 2019 Apr;56:7-17. doi: 10.1016/j.copbio.2018.07.008. Epub 2018 Aug 13.

Abstract

Secondary plant metabolites are extensively used in today's food industries, for example, as coloring-agents, flavouring-agents or texturizing agents. In particular, metabolites with antioxidative properties find applications as preservatives or anti-browning agents. Today, extraction from plant material represents the major source of these metabolites, but progress in the field of metabolic engineering also enabled the microbial production of these valuable compounds as a more economic and ecological alternative. This review article presents the current state of metabolic engineering of microorganisms for production of plant metabolites with applications in the food industries. We focus on compounds, which are already used in food applications, discuss current limitations of microbial plant metabolite production, and outline strategies on how these challenges can be addressed in the future.

摘要

次生代谢物广泛应用于当今的食品工业,例如作为着色剂、调味剂或质构化剂。特别是具有抗氧化特性的代谢物可用作防腐剂或防褐变剂。如今,从植物材料中提取是这些代谢物的主要来源,但代谢工程领域的进展也使微生物生产这些有价值的化合物成为一种更经济和生态的替代方法。本文综述了微生物代谢工程生产在食品工业中有应用的植物代谢物的现状。我们重点介绍了已经应用于食品的化合物,讨论了微生物植物代谢产物生产的当前局限性,并概述了未来如何应对这些挑战的策略。

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