Chemistry Group, Manipal Centre for Natural Sciences, Manipal Academy of Higher Education, Manipal (MAHE), Udupi 576 104, Karnataka, India.
Faculty of Life Sciences, Division of Biotechnology and Bioinformatics, JSS Academy of Higher Education and Research (JSSAHER), Mysuru 570 015, Karnataka, India.
Sensors (Basel). 2018 Aug 16;18(8):2698. doi: 10.3390/s18082698.
In the present study, we describe the facile synthesis of silver nanoparticles (AgNPs) and their nanostructures functionalized with 2-aminopyrimidine-4,6-diol (APD-AgNPs) for Hg ion detection. The promising colorimetric response of APD-AgNPs to detect Hg ions was visible with naked eyes and spectroscopic changes were examined by using a UV-Visible spectrophotometer. The aggregation of APD-AgNPs upon addition of Hg ions was due to the chelation effect of the functionalized nanostructures and results in a color change from pale brown to deep yellow color. The probing sensitivity was observed within five minutes with a detection limit of about 0.35 µM/L. The TEM images of APD-AgNPs showed polydispersed morphologies with hexagonal, heptagonal and spherical nanostructures with an average size between 10 to 40 nm. Furthermore, the sensing behavior of APD-AgNPs towards Hg ions detection was investigated using docking and interaction studies.
在本研究中，我们描述了银纳米粒子（AgNPs）的简便合成及其与 2-氨基嘧啶-4,6-二醇（APD-AgNPs）的纳米结构的功能化，用于 Hg 离子检测。APD-AgNPs 对 Hg 离子的有前景的比色响应可以用肉眼观察到，并且使用紫外可见分光光度计检查了光谱变化。由于功能化纳米结构的螯合效应，AgNPs 的聚集导致颜色从浅棕色变为深黄色。探测灵敏度在五分钟内观察到，检测限约为 0.35 µM/L。APD-AgNPs 的 TEM 图像显示出具有平均尺寸在 10 至 40nm 之间的六边形、七边形和球形纳米结构的多分散形态。此外，还通过对接和相互作用研究研究了 APD-AgNPs 对 Hg 离子检测的传感行为。
