Ghobadi Hassan, Amirajam Zahra, Habibzadeh Afshin
Department of Internal Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
Tanaffos. 2018 Jan;17(1):53-56.
Massive pulmonary thromboembolism (PTE) has an increased risk of mortality. Thrombolytic therapy is the accepted treatment. Reteplase, a variant of tissue plasminogen activator, has been used in acute myocardial infarction with acceptable safety and efficacy, but studies in massive PTE are rare. In this study we report five cases of successful treatment of massive PTE with reteplase.
大面积肺血栓栓塞症(PTE)的死亡风险增加。溶栓治疗是公认的治疗方法。瑞替普酶是组织型纤溶酶原激活剂的一种变体,已用于急性心肌梗死,安全性和疗效尚可,但在大面积PTE方面的研究较少。在本研究中,我们报告了5例使用瑞替普酶成功治疗大面积PTE的病例。