Huerre-Jeanpierre C, Henry I, Bernard M, Gallano P, Weil D, Grzeschik K H, Ramirez F, Junien C
Hum Genet. 1986 May;73(1):64-7. doi: 10.1007/BF00292666.
A recombinant probe specific for the pro alpha 2 chain of human Type V collagen has been used for the localization of the corresponding gene (COL5A2) to chromosome 2. Regional mapping by in situ hybridization and analysis of DNA from human X rodent cell lines indicated that COL5A2 is confined within the segment 2q14----2q32, thus syntenic to the pro alpha 1 (III) collagen gene (COL3A1).
一种针对人V型胶原α2前体链的重组探针已被用于将相应基因(COL5A2)定位到2号染色体上。通过原位杂交进行区域定位以及对人-啮齿动物细胞系DNA的分析表明,COL5A2局限于2q14----2q32区段内,因此与α1(III)前胶原基因(COL3A1)同线。