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冻伤伴后送延迟的病例报告:现场使用伊洛前列素可能改善了预后。

Case Report of Frostbite with Delay in Evacuation: Field Use of Iloprost Might Have Improved the Outcome.

作者信息

Irarrázaval Sebastián, Besa Pablo, Cauchy Emmanuel, Pandey Prativa, Vergara Jorge

机构信息

1 Orthopaedics Surgery Department, School of Medicine, Pontificia Universidad Católica de Chile , Santiago, Chile .

2 Institut de Formation et de Recherche en Médecine de Montagne, Hôpital de Chamonix , Chamonix, France .

出版信息

High Alt Med Biol. 2018 Dec;19(4):382-387. doi: 10.1089/ham.2018.0027. Epub 2018 Aug 17.

Abstract

Frostbite is a common injury in high altitude medicine. Intravenous vasodilators have a proven efficacy and, recently, have been proposed as a safe outpatient treatment. Nevertheless, the lack of availability and consequently delayed application of this treatment option can result in poor clinical outcomes for patients. We present the case of a 60-year-old Chilean man with severe frostbite injuries suffered while climbing Mount Everest. The patient was initially given field treatment to the extent permitted by conditions and consensus guidelines. Unfortunately, advanced management was delayed, with iloprost administered 75 hours after the initial injury. The patient also underwent 5 days of hyperbaric and analgesic/antibiotic therapies. An early bone scan predicted a poor clinical outcome, and five of the patient's fingers, between both hands, were incompletely amputated. We present this case to exemplify the importance of advanced in-field management of frostbite injuries.

摘要

冻伤是高原医学中的常见损伤。静脉血管扩张剂已被证实有效,最近有人提议将其作为一种安全的门诊治疗方法。然而,由于缺乏这种治疗选择以及随后治疗的延迟应用,可能会导致患者临床预后不佳。我们报告一例60岁智利男子在攀登珠穆朗玛峰时遭受严重冻伤的病例。患者最初在条件和共识指南允许的范围内接受了现场治疗。不幸的是,高级治疗被推迟,在初次受伤75小时后才给予伊洛前列素治疗。患者还接受了5天的高压氧和镇痛/抗生素治疗。早期骨扫描预测临床预后不佳,患者双手共有五根手指进行了不完全截肢。我们展示此病例以例证冻伤损伤现场高级管理的重要性。

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