Wang Xi-Hua, Li Min, Cheng Yue, Wang Guang-Jian, Lin Guo-Le, Liu Wei-Nan
Department of General Surgery, Peking Union Medical College Hospital and Chinese Academy of Medical Sciences, Beijing 100730, China.
Department of Nursing, Peking Union Medical College Hospital and Chinese Academy of Medical Sciences, Beijing 100730, China.
World J Clin Cases. 2023 Dec 6;11(34):8219-8227. doi: 10.12998/wjcc.v11.i34.8219.
Frostbite is becoming increasingly common in urban environments, and severe cases can lead to tissue loss. The treatment goal is to preserve tissue and function; the sooner appropriate treatment is administered, the more tissue can be saved. However, not every patient with deep frostbite seeks medical care promptly.
We report the case of a 73-year-old male patient who was lost in the wilderness for 2 d due to trauma and confusion. He experienced deep frostbite on multiple fingers. Treatment should not be discontinued for patients with deep frostbite who present after the optimum treatment timing. Bullae that no longer form (bloody) blisters within 24 h of aspiration should be removed. Mucopolysaccharide polysulfate cream has clinical value in frostbite treatment. The patient was transferred to Chinese Academy of Medical Sciences and Peking Union Medical College Hospital 12 h after being rescued. The patient had contraindications for thrombolysis, the most effective treatment, due to intracranial hemorrhage and presenting past the optimum treatment timing. We devised a comprehensive treatment plan, which involved delayed use vasodilators and high-pressure oxygen therapy at day 49 post-injury. We experimented with mucopolysaccharide polysulfate cream to treat the frostbite. The aim of the treatment was to safeguard as much tissue as possible. In the end, the fingers that suffered from frostbite were able to be partially preserved.
The case indicated that patients with severe frostbite who missed the optimal treatment time and had contraindications for thrombolysis could still partially preserve the affected limbs through comprehensive treatment.
冻伤在城市环境中越来越常见,严重病例可导致组织丧失。治疗目标是保留组织和功能;尽早给予适当治疗,就能挽救更多组织。然而,并非每个深度冻伤患者都会及时就医。
我们报告一例73岁男性患者,因外伤和意识混乱在野外迷路2天。他多个手指遭受深度冻伤。对于错过最佳治疗时机后就诊的深度冻伤患者,治疗不应中断。抽吸后24小时内不再形成(血性)水疱的大疱应予以清除。多磺酸粘多糖乳膏在冻伤治疗中有临床价值。患者获救后12小时被转至中国医学科学院北京协和医院。由于颅内出血且错过最佳治疗时机,患者存在溶栓治疗(最有效治疗方法)的禁忌证。我们制定了综合治疗方案,包括在受伤后第49天延迟使用血管扩张剂和高压氧治疗。我们试用多磺酸粘多糖乳膏治疗冻伤。治疗目的是尽可能多地保留组织。最终,冻伤手指得以部分保留。
该病例表明,错过最佳治疗时间且有溶栓禁忌证的严重冻伤患者,通过综合治疗仍可部分保留患肢。