Turk J Med Sci. 2018 Aug 16;48(4):840-844. doi: 10.3906/sag-1803-183.
BACKGROUND/AIM: Systemic lupus erythematosus (SLE) frequently affects the small joints of the hand and may result in difficulty in activities of daily living. There are very few studies evaluating the problems encountered in the hands in patients with SLE. The aim of this study is to evaluate hand functions in patients with SLE and compare them with rheumatoid arthritis (RA) patients and healthy subjects.
A total 46 female patients meeting the SLE classification criteria were recruited. Similarly, 51 female RA patients and 46 healthy female subjects served as the control groups. To assess the upper extremity disability level, the Disability Arm Shoulder and Hand Questionnaire (DASH) was used. Some functional performances such as hand grip and pinch strength were evaluated using a dynamometer and the Nine Hole Peg Test (NHPT), respectively.
Hand functions were found to be impaired in both SLE and RA patients when compared to healthy controls. In addition, patients with SLE showed better performance in the NHPT, hand grip, and pinch strength than RA patients (P < 0.05). However, the patient-reported disability level was similar in both patient groups (P > 0.05).
Similar to patients with RA, hand functions are significantly impaired in patients with SLE in daily activities.
背景/目的：系统性红斑狼疮（SLE）常累及手部小关节，可能导致日常生活活动困难。目前评估 SLE 患者手部问题的研究很少。本研究旨在评估 SLE 患者的手部功能，并与类风湿关节炎（RA）患者和健康受试者进行比较。
共招募了 46 名符合 SLE 分类标准的女性患者。同样，51 名女性 RA 患者和 46 名健康女性作为对照组。为了评估上肢残疾程度，使用残疾手臂肩手问卷（DASH）进行评估。使用测力计评估手部握力和捏力等一些功能表现，分别使用九孔钉测试（NHPT）进行评估。
与健康对照组相比，SLE 和 RA 患者的手部功能均受损。此外，SLE 患者在 NHPT、握力和捏力方面的表现优于 RA 患者（P<0.05）。然而，两组患者的患者报告残疾程度相似（P>0.05）。
与 RA 患者一样，SLE 患者的手部功能在日常活动中也明显受损。
