Mendelson J H, Mello N K, Ellingboe J, Skupny A S, Lex B W, Griffin M
J Pharmacol Exp Ther. 1986 Jun;237(3):862-6.
Smoking a single 1-g marihuana cigarette containing 1.8% delta 9-tetrahydrocannabinol induced a 30% suppression of plasma luteinizing hormone levels (P less than .02) in women during the luteal phase of the menstrual cycle. After marihuana placebo cigarette smoking, no luteinizing hormone suppression was observed in the same women under double-blind conditions. Marihuana may have adverse effects upon reproductive function during the luteal phase of the menstrual cycle as a consequence of gonadotropin inhibition.
在月经周期的黄体期,女性吸食一支含有1.8% Δ⁹ - 四氢大麻酚的1克大麻香烟,会导致血浆黄体生成素水平抑制30%(P < 0.02)。在双盲条件下,同一批女性吸食大麻安慰剂香烟后,未观察到黄体生成素受到抑制。由于促性腺激素受到抑制,大麻可能会在月经周期的黄体期对生殖功能产生不利影响。