Tuberculosis: Today's researches-tomorrow's therapies.
作者信息
Singh Amit, Surolia Avadhesha
机构信息
Department of Microbiology and Cell Biology, Centre for Infectious Disease Research, Indian Institute of Science, Bangalore, Karnataka, India.
Molecular Biophysics, Indian Institute of Science, Bangalore, Karnataka, India.
出版信息
IUBMB Life. 2018 Sep;70(9):814-817. doi: 10.1002/iub.1909. Epub 2018 Aug 18.
Abstract
摘要
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本文引用的文献
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Mycobacterium tuberculosis: Surviving and Indulging in an Unwelcoming Host.结核分枝杆菌：在不适宜的宿主中生存和放纵。
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Alternate splicing of transcripts upon Mycobacterium tuberculosis infection impacts the expression of functional protein domains.分枝杆菌感染时转录本的可变剪接影响功能蛋白结构域的表达。
IUBMB Life. 2018 Sep;70(9):845-854. doi: 10.1002/iub.1887. Epub 2018 Aug 18.
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Elucidating the role of (p)ppGpp in mycobacterial persistence against antibiotics.阐明（p）ppGpp 在分枝杆菌对抗生素的持续存在中的作用。
IUBMB Life. 2018 Sep;70(9):836-844. doi: 10.1002/iub.1888. Epub 2018 Aug 9.
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Have we realized the full potential of β-lactams for treating drug-resistant TB?我们是否已经充分挖掘了β-内酰胺类药物治疗耐药性结核病的潜力？
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Targeting the messengers: Serine/threonine protein kinases as potential targets for antimycobacterial drug development.靶向信使：丝氨酸/苏氨酸蛋白激酶作为抗分枝杆菌药物开发的潜在靶点。
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Drug permeation and metabolism in Mycobacterium tuberculosis: Prioritising local exposure as essential criterion in new TB drug development.结核分枝杆菌中的药物渗透和代谢：将局部暴露作为新结核药物开发的重要标准。
IUBMB Life. 2018 Sep;70(9):926-937. doi: 10.1002/iub.1866. Epub 2018 Jun 22.
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Redox-guided small molecule antimycobacterials.氧化还原导向的小分子抗分枝杆菌化合物。
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Recent advances for identification of new scaffolds and drug targets for Mycobacterium tuberculosis.最近在鉴定新型结核分枝杆菌支架和药物靶点方面的进展。
IUBMB Life. 2018 Sep;70(9):905-916. doi: 10.1002/iub.1863. Epub 2018 May 14.
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