转导至米尔希尔2型或E26白血病病毒基因组中的原癌基因的分散染色体定位。
Dispersed chromosomal localization of the proto-oncogenes transduced into the genome of Mill Hill 2 or E26 leukemia virus.
作者信息
Symonds G, Quintrell N, Stubblefield E, Bishop J M
出版信息
J Virol. 1986 Jul;59(1):172-5. doi: 10.1128/JVI.59.1.172-175.1986.
Abstract
Both Mill Hill 2 and E26 retroviruses have transduced two cellular genes--c-myc and c-mil/mht (Mill Hill 2) and c-myb and c-ets (E26). We localized the genes transduced by these viruses to different chromosomes: c-myc and c-myb to relatively large chromosomes and c-mil/mht and c-ets to microchromosomes. Thus, like avian erythroblastosis virus, each of these retroviruses has transduced two cellular genes unlinked in the chicken genome.
摘要
米尔希尔2型和E26逆转录病毒都转导了两个细胞基因——c-myc和c-mil/mht（米尔希尔2型）以及c-myb和c-ets（E26）。我们将这些病毒转导的基因定位到不同的染色体上：c-myc和c-myb定位于相对较大的染色体，而c-mil/mht和c-ets定位于微染色体。因此，与禽成红细胞增多症病毒一样，这些逆转录病毒中的每一种都转导了鸡基因组中不连锁的两个细胞基因。
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