Whitfill C E, Akbar W J, Gyles N R, Thoma J A
J Natl Cancer Inst. 1986 Jun;76(6):1185-91.
The development of histocompatible White Leghorn (progressor) and Arkansas Regression (regressor) chicken lines was described. When challenged with Rous sarcoma virus, progressor chickens developed fatal tumors while the regressor chickens eliminated the sarcoma. When sensitized histocompatible peritoneal macrophages and blood lymphocytes were transferred from regressor donors to progressor recipients, they both eradicated growing tumors. Histoincompatible cells were ineffective in inducing tumor remission. Within the two age groups tested, the sensitized blood lymphocytes and macrophages were only effective when transferred between age-matched donor and recipient chickens.
本文描述了组织相容性白来航鸡（进展型）和阿肯色回归鸡（回归型）品系的培育过程。当用劳斯肉瘤病毒攻击时，进展型鸡会患上致命肿瘤，而回归型鸡则能清除肉瘤。当将致敏的组织相容性腹膜巨噬细胞和血液淋巴细胞从回归型供体转移到进展型受体时，它们都能根除正在生长的肿瘤。组织不相容的细胞在诱导肿瘤缓解方面无效。在测试的两个年龄组中，致敏的血液淋巴细胞和巨噬细胞只有在年龄匹配的供体和受体鸡之间转移时才有效。
