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归因于意大利罗马大都市 PM 暴露的心肺疾病的死亡率和发病率。

Mortality and morbidity for cardiopulmonary diseases attributed to PM exposure in the metropolis of Rome, Italy.

机构信息

Italian National Agency for New Technologies, Energy and Sustainable Economic Development, Rome, Italy.

Department of Biology, Sultan Qaboos University, Al-Khould, Muscat, Oman.

出版信息

Eur J Intern Med. 2018 Nov;57:49-57. doi: 10.1016/j.ejim.2018.07.027. Epub 2018 Aug 16.

Abstract

The aim of the study was to evaluate the health effects associated with the exposure to ground-level of particulate matters with aerodynamic diameter ≤ 2.5 μm (PM) on citizens in Rome (Italy) in 2015 and 2016. Based on the new version of the World Health Organization's AirQ+ model, we have estimated the short- and long-term effects of PM on hospital admissions due to cardiovascular (HA-CVD) and respiratory diseases (HA-RD) as well as on mortality for ischemic heart disease (M-IHD) and chronic obstructive pulmonary disease (M-COPD). In this study, city-specific relative risk values and baseline incidence rates were used to calculate the association between PM and daily counts of emergency hospitalizations and mortality. The annual mean PM concentrations were 18 μg m and 14 μg m in 2015 and 2016, respectively. In Rome, the citizens are mostly exposed to daily mean PM concentrations of 10-20 μg m during the study period. In 2015-2016, 0.4-0.6% for HA-CVD, 1.1-1.5% for HA-RD, 16.5-18.1% for M-IHD and 8.5-9.2% for M-COPD are attributed to PM. In 2015-2016, 134-186 HA-CVD, 126-175 HA-RD, 947-1037 M-IHD and 244-279 M-COPD, caused by PM exposure, could be "avoided" if PM concentrations would not exceed 10 μg m, i.e. the threshold recommended by the World Health Organization. Thus, a consistent air quality management and sustainable city planning are needed, urgently, to mitigate the adverse effects of PM exposure in Rome.

摘要

本研究旨在评估 2015 年和 2016 年罗马(意大利)市民接触地面水平细颗粒物(PM)与心血管疾病(HA-CVD)和呼吸道疾病(HA-RD)住院以及缺血性心脏病(M-IHD)和慢性阻塞性肺疾病(M-COPD)死亡率之间的健康关联。基于世界卫生组织(WHO)空气质素指数+(AirQ+)模型的新版本,我们估计了 PM 对心血管疾病(HA-CVD)和呼吸道疾病(HA-RD)住院的短期和长期影响,以及对缺血性心脏病(M-IHD)和慢性阻塞性肺疾病(M-COPD)死亡率的影响。在本研究中,使用城市特定的相对风险值和基线发病率来计算 PM 与每日急症住院和死亡率之间的关联。2015 年和 2016 年的年平均 PM 浓度分别为 18μg/m3和 14μg/m3。在罗马,研究期间市民主要接触的 PM 日平均浓度为 10-20μg/m3。2015-2016 年,归因于 PM 的 HA-CVD 占 0.4-0.6%,HA-RD 占 1.1-1.5%,M-IHD 占 16.5-18.1%,M-COPD 占 8.5-9.2%。如果 PM 浓度不超过 10μg/m3,即世界卫生组织推荐的阈值,那么 2015-2016 年,可避免因 PM 暴露而导致 134-186 例 HA-CVD、126-175 例 HA-RD、947-1037 例 M-IHD 和 244-279 例 M-COPD。因此,需要紧急进行一致的空气质量管理和可持续的城市规划,以减轻罗马 PM 暴露的不良影响。

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