Psychiatric Hospital of the Cross, P.O. Box 60096 Jal Eddib, Lebanon; Faculty of Pharmacy, Saint Joseph University, Beirut, Lebanon; Faculty of Medicine and Medical Sciences, Holy Spirit University of Kaslik (USEK), Jounieh, Lebanon; Faculty of Pharmacy, Lebanese University, Hadath, Lebanon; Occupational Health Environment Research Team, U1219 BPH Bordeaux Population Health Research Center Inserm, Bordeaux University, Bordeaux, France; INSPECT-LB, Institut National de Santé Publique, Épidemiologie Clinique et Toxicologie, Faculty of Public Health, Lebanese University, Beirut, Lebanon.
Psychiatric Hospital of the Cross, P.O. Box 60096 Jal Eddib, Lebanon; Department of Psychology, Holy Spirit University of Kaslik, Kaslik, Lebanon; Faculty of Pedagogy, Lebanese University, Beirut, Lebanon.
Encephale. 2019 Jun;45(3):195-199. doi: 10.1016/j.encep.2018.05.004. Epub 2018 Aug 17.
To use the Arabic version of the MADRS in Lebanese depressed patients, check its validity and reproducibility compared to other versions of the questionnaire and assess risk factors affecting the total MADRS score.
This case-control study, performed between September 2016 and January 2017, included 200 patients (100 patients, 100 controls). The questionnaire included two parts, the first one concerning the socio-demographic characteristics another one that included the Montgomery-Asberg Depression Rating Scale (MADRS) questions, which was translated from English to Arabic through an initial translation and back translation process.
The MADRS scale items converged over a solution of one factor that had an Eigenvalue over 1, explaining a total of 83.90% of the variance. A Kaiser-Meyer-Olkin measure of sampling adequacy of 0.953 was found, with a significant Bartlett's test of sphericity (P<0.001). A stepwise linear regression, using the total MADRS score as continuous variable, showed that a university level of education would significantly decrease the total MADRS score by 20 points (beta=-20.02, CI: from -26.337 to -13.709, P<0.001). Unemployment was significantly more associated with an increase in the total MADRS score level by 10.23 points (beta=10.23, CI: 3.944-16.526, P=0.002).
This study shows that the Arabic version of the MADRS has promising psychometric properties, and thus it is a good tool to use for the diagnosis of patients with depression. Based on this study, health care professionals and researchers can readily use the MADRS questionnaire to estimate the overall severity of depression among psychiatric patients in Lebanon.
在黎巴嫩抑郁症患者中使用阿拉伯语版 MADRS，检验其与其他版本问卷的有效性和可重复性，并评估影响 MADRS 总分的风险因素。
这项病例对照研究于 2016 年 9 月至 2017 年 1 月进行，共纳入 200 例患者（100 例患者，100 例对照）。问卷包括两部分，第一部分为社会人口学特征，另一部分包括蒙哥马利-阿斯伯格抑郁评定量表（MADRS）的问题，该量表通过初步翻译和回译过程从英语翻译为阿拉伯语。
MADRS 量表各条目在一个特征值大于 1 的解中收敛，共解释了 83.90%的方差。Kaiser-Meyer-Olkin 样本充分性度量值为 0.953，Bartlett 球形检验显著（P<0.001）。采用逐步线性回归，以 MADRS 总分作为连续变量，发现大学学历会使 MADRS 总分显著降低 20 分（β=-20.02，CI：-26.337 至-13.709，P<0.001）。失业与 MADRS 总分水平增加显著相关，增加 10.23 分（β=10.23，CI：3.944 至 16.526，P=0.002）。
本研究表明，阿拉伯语版 MADRS 具有良好的心理测量学特性，是一种诊断抑郁症患者的良好工具。基于本研究，卫生保健专业人员和研究人员可以方便地使用 MADRS 问卷来评估黎巴嫩精神科患者的抑郁严重程度。
