Tischer Bernd, Mehl Andrea
Kantar Health GmbH, Munich, Germany,
Sandoz International GmbH, Holzkirchen, Germany.
Patient Prefer Adherence. 2018 Aug 2;12:1413-1424. doi: 10.2147/PPA.S169339. eCollection 2018.
This survey investigated patients' and nurses' preferences among four different autoinjectors used for subcutaneous delivery of medication for rheumatoid arthritis (RA).
In a multinational survey in five countries, 200 patients with RA and 100 nurses training patients on the use of autoinjectors participated in face-to-face interviews. Respondents were asked to rate the importance of eleven autoinjector attributes and to compare the autoinjectors for etanercept (Enbrel, MyClic autoinjector), adalimumab (Humira, Humira pen), and an etanercept biosimilar (Benepali, Molly autoinjector) with a demonstration autoinjector for a new etanercept biosimilar - Erelzi (SensoReady autoinjector).
Easy grip and ease of performing self-injection were the most important attributes identified by both groups. Overall, 79% of the patients rated the SensoReady autoinjector easier to use than their currently used injection device (86% of MyClic users, 84% of Humira pen users, and 63% of Molly users). In the patient survey, the SensoReady performed better than the other autoinjectors on the attributes visual feedback after completion of injection, easy to grip, and convenient shape. Nurses also rated the SensoReady easier to use than the MyClic (95%), Humira pen (97%), or Molly (91%). When asked which autoinjector they would recommend to a patient with RA who had not used an autoinjector before, 81% of patients and 90% of nurses selected the SensoReady.
Both patients and nurses perceived the SensoReady to be easier to use compared with other available injection devices. The main reasons for this preference were the buttonless injection, 360° viewing window for feedback (visual confirmation of dose injection), and convenient triangular shape making the injection device easy to grip. Patients and nurses were most likely to recommend the SensoReady autoinjector over other autoinjectors to patients with RA.
本调查研究了类风湿关节炎(RA)患者和护士在用于皮下注射药物的四种不同自动注射器中的偏好。
在五个国家开展的一项跨国调查中,200名类风湿关节炎患者和100名培训患者使用自动注射器的护士参与了面对面访谈。受访者被要求对自动注射器的11个属性的重要性进行评分,并将用于注射依那西普(恩利,MyClic自动注射器)、阿达木单抗(修美乐,修美乐笔)和一种依那西普生物类似药(安佰诺,Molly自动注射器)的自动注射器与一种用于新的依那西普生物类似药——依瑞可(SensoReady自动注射器)的示范自动注射器进行比较。
易于握持和便于自行注射是两组受访者确定的最重要属性。总体而言,79%的患者认为SensoReady自动注射器比他们目前使用的注射装置更易于使用(MyClic用户中的86%、修美乐笔用户中的84%以及Molly用户中的63%)。在患者调查中,SensoReady在注射完成后的视觉反馈、易于握持和形状方便等属性方面表现优于其他自动注射器。护士们也认为SensoReady比MyClic(95%)、修美乐笔(97%)或Molly(91%)更易于使用。当被问及他们会向之前未使用过自动注射器的类风湿关节炎患者推荐哪种自动注射器时,81%的患者和90%的护士选择了SensoReady。
与其他可用的注射装置相比,患者和护士都认为SensoReady更易于使用。这种偏好的主要原因是无按钮注射、用于反馈的360°观察窗(剂量注射的视觉确认)以及方便的三角形形状使注射装置易于握持。患者和护士最有可能向类风湿关节炎患者推荐SensoReady自动注射器而非其他自动注射器。