• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

真核生物核糖体RNA基因的转录

Transcription of eukaryotic ribosomal RNA gene.

作者信息

Jacob S T

出版信息

Mol Cell Biochem. 1986 Apr;70(1):11-20. doi: 10.1007/BF00233800.

DOI:10.1007/BF00233800
PMID:3012322
Abstract

Remarkable advances have been made in the identification of the promoter regions for the ribosomal RNA genes from lower and higher eukaryotes. There has been some progress in the elucidation of the factors that control transcription of the ribosomal RNA gene. The characterization of the transcription factors are crucial for the understanding of the molecular mechanisms of ribosomal gene expression.

摘要

在鉴定低等和高等真核生物核糖体RNA基因的启动子区域方面已经取得了显著进展。在阐明控制核糖体RNA基因转录的因子方面也取得了一些进展。转录因子的特性对于理解核糖体基因表达的分子机制至关重要。

相似文献

1
Transcription of eukaryotic ribosomal RNA gene.真核生物核糖体RNA基因的转录
Mol Cell Biochem. 1986 Apr;70(1):11-20. doi: 10.1007/BF00233800.
2
Readthrough enhancement and promoter occlusion on the ribosomal genes of Xenopus laevis.非洲爪蟾核糖体基因上的通读增强和启动子阻遏
Biochem Cell Biol. 1992 May;70(5):324-31. doi: 10.1139/o92-050.
3
A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter.非洲爪蟾RNA聚合酶I的一个终止位点也作为相邻启动子的一个元件。
Cell. 1986 Dec 26;47(6):913-20. doi: 10.1016/0092-8674(86)90806-8.
4
Transcriptional regulation of mammalian ribosomal RNA genes.
Bioessays. 1985 Dec;3(6):263-5. doi: 10.1002/bies.950030609.
5
An RNA polymerase I termination site can stimulate the adjacent ribosomal gene promoter by two distinct mechanisms in Xenopus laevis.在非洲爪蟾中，RNA聚合酶I终止位点可通过两种不同机制刺激相邻的核糖体基因启动子。
Genes Dev. 1990 Jul;4(7):1240-51. doi: 10.1101/gad.4.7.1240.
6
Transcription of cloned eukaryotic ribosomal RNA genes.克隆真核生物核糖体RNA基因的转录
Annu Rev Biochem. 1986;55:801-30. doi: 10.1146/annurev.bi.55.070186.004101.
7
Ribosomal gene promoter domains can function as artificial enhancers of RNA polymerase I transcription, supporting a promoter origin for natural enhancers in Xenopus.核糖体基因启动子结构域可作为RNA聚合酶I转录的人工增强子，这支持了非洲爪蟾中天然增强子的启动子起源。
Proc Natl Acad Sci U S A. 1994 Jan 18;91(2):464-8. doi: 10.1073/pnas.91.2.464.
8
Xenopus ribosomal gene enhancers function when inserted inside the gene they enhance.
Nucleic Acids Res. 1985 Dec 20;13(24):8999-9009. doi: 10.1093/nar/13.24.8999.
9
The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF.非洲爪蟾核糖体基因增强子结合一种重要的聚合酶I转录因子，即xUBF。
Genes Dev. 1989 Nov;3(11):1779-88. doi: 10.1101/gad.3.11.1779.
10
A 140-base-pair repetitive sequence element in the mouse rRNA gene spacer enhances transcription by RNA polymerase I in a cell-free system.小鼠rRNA基因间隔区中的一个140个碱基对的重复序列元件在无细胞系统中增强了RNA聚合酶I的转录作用。
Proc Natl Acad Sci U S A. 1990 Oct;87(19):7527-31. doi: 10.1073/pnas.87.19.7527.

引用本文的文献

1
Self-circularizing 5'-ETS RNAs accumulate along with unprocessed pre ribosomal RNAs in growth-stressed Entamoeba histolytica.在生长压力下的溶组织内阿米巴中，自我环化的 5'-ETS RNA 与未加工的核糖体前 RNA 一起积累。
Sci Rep. 2012;2:303. doi: 10.1038/srep00303. Epub 2012 Mar 6.
2
In vitro transcription of Drosophila rRNA genes shows stimulation by a phorbol ester and serum.果蝇核糖体RNA基因的体外转录显示受佛波酯和血清的刺激。
Mol Cell Biol. 1993 Feb;13(2):934-41. doi: 10.1128/mcb.13.2.934-941.1993.
3
Molecular and biochemical features of poly (ADP-ribose) metabolism.

本文引用的文献

1
Multiple factors required for accurate initiation of transcription by purified RNA polymerase II.纯化的RNA聚合酶II准确起始转录需要多种因素。
J Biol Chem. 1980 Dec 25;255(24):11992-6.
2
Multiple factors are required for the accurate transcription of purified genes by RNA polymerase III.RNA聚合酶III对纯化基因进行准确转录需要多种因素。
J Biol Chem. 1980 Dec 25;255(24):11986-91.
3
A control region in the center of the 5S RNA gene directs specific initiation of transcription: I. The 5' border of the region.5S RNA基因中心的一个控制区域指导转录的特异性起始：I. 该区域的5'边界。
聚（ADP - 核糖）代谢的分子和生化特征
Mol Cell Biochem. 1993 May 26;122(2):171-93. doi: 10.1007/BF01076101.
4
Regulation of ribosomal gene transcription.核糖体基因转录的调控
Biochem J. 1995 Mar 15;306 ( Pt 3)(Pt 3):617-26. doi: 10.1042/bj3060617.
5
DNA binding properties of a 110 kDa nucleolar protein.一种110千道尔顿核仁蛋白的DNA结合特性。
Nucleic Acids Res. 1986 Sep 11;14(17):6803-20. doi: 10.1093/nar/14.17.6803.
6
On the early evolution of RNA polymerase.论RNA聚合酶的早期进化。
J Mol Evol. 1988;27(4):365-76. doi: 10.1007/BF02101199.
7
The mouse ribosomal gene terminator consists of three functionally separable sequence elements.小鼠核糖体基因终止子由三个功能上可分离的序列元件组成。
EMBO J. 1988 May;7(5):1497-502. doi: 10.1002/j.1460-2075.1988.tb02968.x.
8
Purification and characterization of a novel factor which stimulates rat ribosomal gene transcription in vitro by interacting with enhancer and core promoter elements.一种通过与增强子和核心启动子元件相互作用在体外刺激大鼠核糖体基因转录的新型因子的纯化与鉴定。
Mol Cell Biol. 1990 Oct;10(10):5177-86. doi: 10.1128/mcb.10.10.5177-5186.1990.
9
The nucleotide sequence of the entire ribosomal DNA operon and the structure of the large subunit rRNA of Giardia muris.微小贾第虫核糖体DNA操纵子的全核苷酸序列及大亚基rRNA的结构
J Mol Evol. 1992 Oct;35(4):318-28. doi: 10.1007/BF00161169.
Cell. 1980 Jan;19(1):13-25. doi: 10.1016/0092-8674(80)90384-0.
4
Transcription of mouse rRNA genes by RNA polymerase I: in vitro and in vivo initiation and processing sites.RNA聚合酶I对小鼠rRNA基因的转录：体外和体内的起始及加工位点
Cell. 1981 Nov;27(1 Pt 2):165-74. doi: 10.1016/0092-8674(81)90370-6.
5
Activation of purified hepatoma RNA polymerase I by homologous protein kinase NII.同源蛋白激酶NII对纯化的肝癌RNA聚合酶I的激活作用。
J Biol Chem. 1981 Nov 10;256(21):10755-8.
6
Assembly of transcriptionally active 5S RNA gene chromatin in vitro.体外转录活性5S RNA基因染色质的组装
Cell. 1982 Apr;28(4):781-91. doi: 10.1016/0092-8674(82)90057-5.
7
Fractionation and reconstitution of factors required for accurate transcription of mammalian ribosomal RNA genes: identification of a species-dependent initiation factor.哺乳动物核糖体RNA基因精确转录所需因子的分级分离与重组：一种物种依赖性起始因子的鉴定
Nucleic Acids Res. 1982 Nov 11;10(21):6659-70. doi: 10.1093/nar/10.21.6659.
8
In vitro transcription of human ribosomal RNA genes by RNA polymerase I.RNA聚合酶I对人类核糖体RNA基因的体外转录
J Mol Appl Genet. 1982;1(6):575-84.
9
Separation and characterization of factors mediating accurate transcription by RNA polymerase II.介导RNA聚合酶II精确转录的因子的分离与特性分析。
J Biol Chem. 1982 Dec 10;257(23):14419-27.
10
Transcription of Xenopus ribosomal RNA genes by RNA polymerase I in vitro.爪蟾核糖体RNA基因在体外由RNA聚合酶I进行转录。
J Biol Chem. 1982 Dec 10;257(23):14375-83.