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非手术治疗对颞下颌关节紊乱症是否有效?——一项系统评价与荟萃分析

Is nonsurgical management effective in temporomandibular joint disorders? - A systematic review and meta-analysis.

作者信息

Nandhini J, Ramasamy S, Ramya K, Kaul Ronak Nazir, Felix A John William, Austin Ravi David

机构信息

Department of Oral Medicine and Radiology, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram, India.

Department of Oral and Maxillofacial Surgery, Sri Ramakrishna Dental College and Hospital, Coimbatore, Tamil Nadu, India.

出版信息

Dent Res J (Isfahan). 2018 Jul-Aug;15(4):231-241.

Abstract

BACKGROUND

Various nonsurgical interventions have been used for the management of patients with temporomandibular joint (TMJ) disorders, but their clinical effectiveness remains unclear. Hence, the purpose of this systematic review and meta-analyses was to assess the evidence of the effectiveness of nonsurgical interventions in the management of TMJ disorders.

MATERIALS AND METHODS

A literature search on five databases such as PubMed, PubMed Central Cochrane, TRIP, NGCH databases and hand searching was conducted for a period from October 1995 to 2015. Randomized control trials (RCTs) on the nonsurgical management of TMJ disorders were included and reported in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The quality of the articles was assessed by JADAD scoring. Finally, out of 23 RCTs, 11 articles having any of the primary outcomes (pain pressure threshold [PPT], pain, maximal pain-free mouth opening, and level of dysfunction) were selected. The extracted data were analyzed using NCSS software.

RESULTS

The results showed the evidence of pain reduction ( = 0.00), maximal pain-free mouth opening ( = 0.0138), and decrease in level of dysfunction ( = 0.0007) but no improvement in PPT to a significant level ( = 0.6600).

CONCLUSION

Our results suggest that the simplest, cost-effective nonsurgical treatments have a positive therapeutic effect on the initial management of TMJ disorders. However, a consistent methodology recording both the objective and subjective outcomes would be a better choice for added reliability.

摘要

背景

多种非手术干预方法已用于颞下颌关节(TMJ)疾病患者的治疗,但其临床疗效仍不明确。因此,本系统评价和荟萃分析的目的是评估非手术干预在治疗TMJ疾病有效性方面的证据。

材料与方法

对PubMed、PubMed Central Cochrane、TRIP、NGCH数据库等五个数据库进行了1995年10月至2015年期间的文献检索,并进行了手工检索。纳入了关于TMJ疾病非手术治疗的随机对照试验(RCT),并按照系统评价和荟萃分析的首选报告项目指南进行报告。通过JADAD评分评估文章质量。最后,在23项RCT中,选择了11篇具有任何主要结局(疼痛压力阈值[PPT]、疼痛、最大无痛开口度和功能障碍水平)的文章。使用NCSS软件对提取的数据进行分析。

结果

结果显示有证据表明疼痛减轻(P = 0.00)、最大无痛开口度增加(P = 0.0138)和功能障碍水平降低(P = 0.0007),但PPT没有显著改善(P = 0.6600)。

结论

我们的结果表明,最简单、具有成本效益的非手术治疗对TMJ疾病的初始治疗具有积极的治疗效果。然而,采用一致的方法记录客观和主观结局将是提高可靠性的更好选择。

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