Division of Applied Chemistry, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Nakamachi, Koganei 184-8588, Japan.
Department of Biomolecular Functional Engineering, Ibaraki University, Nakanarusawa 4-12-1, Hitachi 316-8511, Japan.
Chem Commun (Camb). 2018 Sep 14;54(71):9913-9916. doi: 10.1039/c8cc05458d. Epub 2018 Aug 20.
Crossed aldol reactions of the CF-containing pseudo C symmetric cyclic imide 3 were carried out by way of the corresponding boron bisenolate to stereoselectively furnish the desired products 4 and this procedure allowed the preferential construction of the diastereomers of the compounds previously obtained from the acyclic counterpart 1.
含 CF 的拟 C 对称环酰亚胺 3 通过相应的硼双酚盐进行交叉羟醛反应，立体选择性地提供所需产物 4，该方法允许优先构建先前从非环对应物 1 获得的化合物的非对映异构体。
