Wu Jingwen, Yang Lan, Li Yuanjing, Guo Luhua
Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangzhou 510140, P.R.China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2018 Aug 25;35(4):647-650. doi: 10.7507/1001-5515.201706091.
Bioactive glass (BG) has been widely used in bone tissue engineering due to its good osteogenic property and bioactivity, but it still has some deficiencies, such as poor cell adhesion and low osteogenic rate and so on. Mesoporous biological glass (MBG) is a kind of new material originated from BG and mesoporous silica (MS). Because of its large number of nano-channel, large specific surface area, easy degradation, good biocompatibility and biological activity, MBG has great application prospects in the field of bone tissue engineering. This review would present MBG preparation and experimental research in order to provide the theoretical basis and experimental reference for related researches.
生物活性玻璃(BG)因其良好的成骨性能和生物活性而被广泛应用于骨组织工程,但它仍存在一些不足,如细胞黏附性差、成骨率低等。介孔生物玻璃(MBG)是一种源自BG和介孔二氧化硅(MS)的新型材料。由于其具有大量的纳米通道、大比表面积、易于降解、良好的生物相容性和生物活性,MBG在骨组织工程领域具有广阔的应用前景。本文综述将介绍MBG的制备及实验研究,以便为相关研究提供理论依据和实验参考。