Author Affiliations: School of Nursing, Shanghai JiaoTong University, China (Dr Liu); School of Nursing, Fudan University (Dr Yuan), Shanghai, China; Division of Biostatistics and Study Methodology (Dr Wang), Department of Nursing Research and Quality Outcomes (Dr Hinds), Center for Translational Science, Children's National Health System, Washington, DC; School of Medicine, The George Washington University (Drs Wang and Hinds), Washington, DC; Nursing Department, Shanghai Children's Medical Center Affiliated to Shanghai JiaoTong University School of Medicine (Ms N. Shen), China; and Nursing Department, Children's Hospital of Soochow University (Ms M. Shen), Jiangsu, China.
Cancer Nurs. 2019 Nov/Dec;42(6):430-438. doi: 10.1097/NCC.0000000000000633.
The Pediatric Patient-Reported Outcomes Measurement Information System (PROMIS) was developed to measure symptoms and functions of children with a variety of chronic diseases. As the Chinese version of pediatric PROMIS (C-Ped-PROMIS) measures was developed, the measurement properties of C-Ped-PROMIS have not been demonstrated.
The aim of this study was to examine the reliability, validity, and factorial structure of the C-Ped-PROMIS measures in children with cancer in China.
A total of 272 children and adolescents were recruited from 3 hospitals in China. The 8 C-Ped-PROMIS measures and Pediatric Quality of Life Inventory General Core Module and Cancer Module were administered in a cross-sectional design. Known-group validity, concurrent validity, and item and scale reliability of these 8 measures were examined by using SPSS 21.0, and factorial structures were tested by using confirmatory factor analysis with Mplus 7.1.
All 8 C-Ped-PROMIS measures showed good known-group validity as hypothesized (P < .05) and good concurrent validity measured by significant correlations with the Pediatric Quality of Life Inventory General Core Module and Cancer Module; the correlation coefficients ranged from r = 0.519 to r = 0.655, except for peer relationship with r = 0.255 and r = 0.136, respectively. The Cronbach's α of C-Ped-PROMIS ranged from .758 to .910, and model-estimated scale reliabilities ranged from 0.740 to 0.905. The confirmatory factor analysis models of each measure fit data very well.
All 8 C-Ped-PROMIS measures have a valid factorial structure as theoretically defined with good reliability and validity.
The C-Ped-PROMIS can be readily used to measure symptoms and functions of children and adolescents with cancer in China.
儿科患者报告结局测量信息系统（PROMIS）是为了测量各种慢性疾病儿童的症状和功能而开发的。随着儿科 PROMIS（C-Ped-PROMIS）中文版的开发，其测量性能尚未得到验证。
本研究旨在检验 C-Ped-PROMIS 在我国癌症患儿中的信度、效度和因子结构。
本研究采用横断面设计，共招募了来自中国 3 家医院的 272 名儿童和青少年。在该研究中，8 项 C-Ped-PROMIS 量表和儿科生活质量通用核心模块和癌症模块同时被用于评估。采用 SPSS 21.0 检验这些 8 项测量的已知组有效性、同时效性和项目及量表的信度，采用 Mplus 7.1 进行验证性因子分析来检验因子结构。
所有 8 项 C-Ped-PROMIS 量表均表现出与假设一致的良好已知组有效性（P<0.05）和良好的同时效性，与儿科生活质量通用核心模块和癌症模块呈显著相关（r=0.5190.655），除了同伴关系量表的 r 值分别为 0.255 和 0.136。C-Ped-PROMIS 的 Cronbach's α 值为 0.7580.910，模型估计的量表信度为 0.740~0.905。每个量表的验证性因子分析模型都非常适合数据。
8 项 C-Ped-PROMIS 量表均具有有效理论定义的因子结构，具有良好的信度和效度。
C-Ped-PROMIS 可用于测量中国癌症患儿的症状和功能。
