Li Rongrong, Shen Xinyi, Zhang Lin, Chan Yuying, Yao Wenying, Zhang Guanxun, Li Huiling
School of Nursing, Suzhou Medical College, Soochow University, Suzhou, China.
The Union, Children's Hospital of Soochow University, Suzhou, China.
Asia Pac J Oncol Nurs. 2023 May 12;10(7):100243. doi: 10.1016/j.apjon.2023.100243. eCollection 2023 Jul.
This study aims to explore the application effect of Child Life intervention on pain, anxiety, fatigue, and sleep disturbance in children with acute leukemia.
In a single-blinded, parallel-group randomized controlled trial, 96 children with acute leukemia were randomized to either the intervention group, which received Child Life intervention twice a week for 8 weeks, or the control group, which received routine care. Outcomes were evaluated at baseline and day 3 postintervention.
All of the participants completed the study. Compared with the control group, the intervention group showed a significant reduction in pain, anxiety, fatigue, and sleep disturbance ( < 0.001). However, no significant differences were observed in the disorders of excessive somnolence.
Child Life intervention can effectively improve pain, anxiety, fatigue, and sleep disturbance in children with acute leukemia undergoing chemotherapy. The results suggest that symptom cluster management intervention based on Child Life provided a promising approach for simultaneously treating multiple symptoms within a cluster.
本研究旨在探讨儿童生活干预对急性白血病患儿疼痛、焦虑、疲劳和睡眠障碍的应用效果。
在一项单盲、平行组随机对照试验中，96名急性白血病患儿被随机分为干预组和对照组。干预组每周接受两次儿童生活干预，共8周；对照组接受常规护理。在基线和干预后第3天评估结果。
所有参与者均完成了研究。与对照组相比，干预组的疼痛、焦虑、疲劳和睡眠障碍显著减轻（P<0.001）。然而，在嗜睡障碍方面未观察到显著差异。
儿童生活干预可有效改善接受化疗的急性白血病患儿的疼痛、焦虑、疲劳和睡眠障碍。结果表明，基于儿童生活的症状群管理干预为同时治疗群内多种症状提供了一种有前景的方法。
