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利用单片式柔性垂直 AlGaInP 发光二极管进行毛发生长光刺激。

Trichogenic Photostimulation Using Monolithic Flexible Vertical AlGaInP Light-Emitting Diodes.

机构信息

Department of Materials Science and Engineering , Korea Advanced Institute of Science and Technology (KAIST) , 291 Daehak-ro , Yuseong-gu, Daejeon 34141 , Republic of Korea.

Department of Biological Sciences , Korea Advanced Institute of Science and Technology (KAIST) , 291 Daehak-ro , Yuseong-gu, Daejeon 34141 , Republic of Korea.

出版信息

ACS Nano. 2018 Sep 25;12(9):9587-9595. doi: 10.1021/acsnano.8b05568. Epub 2018 Aug 22.

Abstract

Alopecia is considered an aesthetic, psychological, and social issue among modern people. Although laser-induced skin stimulation is utilized for depilation treatment, such treatment has significant drawbacks of high energy consumption, huge equipment size, and limited usage in daily life. Here, we present a wearable photostimulator for hair-growth applications using high-performance flexible red vertical light-emitting diodes (f-VLEDs). Flexible microscale LEDs were effectively fabricated by a simple monolithic fabrication process, resulting in high light output (∼30 mW mm), low forward voltage (∼2.8 V), and excellent flexibility for wearable biostimulation. Finally, trichogenic stimulation of a hairless mouse was achieved using high-performance red f-VLEDs with high thermal stability, device uniformity, and mechanical durability.

摘要

脱发被认为是现代人的一个美学、心理和社会问题。虽然激光诱导的皮肤刺激被用于脱毛治疗,但这种治疗方法存在能量消耗高、设备体积大以及日常生活中使用受限等显著缺点。在这里,我们提出了一种使用高性能柔性红光垂直发光二极管(f-VLED)的可穿戴光刺激器,用于头发生长应用。通过简单的单片制造工艺有效地制造了柔性微尺度 LED,从而实现了高光输出(约 30 mW mm)、低正向电压(约 2.8 V)和出色的可穿戴生物刺激柔韧性。最后,使用具有高热稳定性、器件均匀性和机械耐久性的高性能红光 f-VLED 实现了无毛小鼠的毛发生长刺激。

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