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亚型的膜表面特征

Membrane Surface Features of Subtypes.

作者信息

Yason John Anthony, Tan Kevin Shyong Wei

机构信息

Laboratory of Cellular and Molecular Parasitology, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077, Singapore.

出版信息

Genes (Basel). 2018 Aug 17;9(8):417. doi: 10.3390/genes9080417.

DOI:10.3390/genes9080417
PMID:30126152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6115916/
Abstract

is a common intestinal protistan parasite with global distribution. is a species complex composed of several isolates with biological and morphological differences. The surface coats of from three different isolates representing three subtypes were analyzed using scanning electron microscopy. This structure contains carbohydrate components that are also present in surface glycoconjugates in other parasitic protozoa. Electron micrographs show variations in the surface coats from the three isolates. These differences could be associated with the differences in the pathogenic potential of subtypes. Apart from the surface coat, a plasma membrane-associated surface antigen has been described for ST7 and is associated with programmed cell death features of the parasite.

摘要

是一种分布于全球的常见肠道原生动物寄生虫。是一个由几种具有生物学和形态学差异的分离株组成的物种复合体。使用扫描电子显微镜分析了代表三种亚型的来自三个不同分离株的表面被膜。这种结构含有碳水化合物成分,这些成分也存在于其他寄生原生动物的表面糖缀合物中。电子显微镜照片显示了来自三种分离株的表面被膜的差异。这些差异可能与亚型的致病潜力差异有关。除了表面被膜外,还描述了一种与质膜相关的表面抗原,它与该寄生虫的程序性细胞死亡特征有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8911/6115916/c62a5fe41264/genes-09-00417-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8911/6115916/08608b9d988b/genes-09-00417-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8911/6115916/c62a5fe41264/genes-09-00417-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8911/6115916/08608b9d988b/genes-09-00417-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8911/6115916/c62a5fe41264/genes-09-00417-g002.jpg

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肠道微生物群相关原生生物的连续完整组装揭示了其对宿主生态的进化多样性。
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