Department of Oral and Maxillofacial Surgery, Parc Taulí University Hospital, Barcelona, Spain.
Department of Oral and Maxillofacial Surgery, Bellvitge University Hospital, L´ Hospitalet de Llobregat, Barcelona, Spain.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jan;127(1):24-29. doi: 10.1016/j.oooo.2018.07.007. Epub 2018 Jul 21.
The aim of this study was to investigate whether the use of a thrombin-fibrinogen biosponge (TachoSil) has any advantage in tongue healing.
A retrospective study with 30 patients treated with partial glossectomy (below half a tongue) was designed. We compared the results from a group using the biosponge (n =15 patients) and a control group (n = 15). Variables taken into consideration were bolus clearance, frenulum flexibility, and oral transit time. With these parameters, we formulated a "tongue remaining functional" (TRF) scale to assess tongue functionality after the surgery. We also evaluated long-term quality of life by using the Functional Intraoral Glasgow Scale (FIGS).
In this study, TRF score, bolus clearance, oral transit time, and frenulum flexibility were significantly improved in the biosponge group. However, there were no differences between the 2 groups in the FIGS scores.
The use of the biosponge in this pilot study showed positive long-term effects in lingual healing and functionality after partial glossectomies.
本研究旨在探讨使用凝血酶-纤维蛋白原生物海绵（TachoSil）是否对舌部愈合有优势。
设计了一项回顾性研究，纳入 30 例接受部分舌切除术（舌的一半以下）的患者。我们比较了使用生物海绵的组（n=15 例患者）和对照组（n=15 例患者）的结果。纳入考虑的变量为团块清除率、舌系带灵活性和口腔通过时间。使用这些参数，我们制定了一个“舌部剩余功能”（TRF）量表，以评估手术后的舌功能。我们还通过使用功能性口腔格拉斯哥量表（FIGS）评估了长期生活质量。
在这项研究中，生物海绵组的 TRF 评分、团块清除率、口腔通过时间和舌系带灵活性均显著改善。然而，FIGS 评分两组间无差异。
在这项初步研究中，使用生物海绵在部分舌切除术后的舌部愈合和功能方面显示出积极的长期效果。
