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T2 期鳞状细胞癌行部分舌切除术的长期功能预后和生活质量。

Long-term functional outcomes and quality of life after partial glossectomy for T2 squamous cell carcinomas.

机构信息

University of Turin, Department of Surgical Sciences, Division of Otorhinolaryngology, Turin, Italy.

University of Turin, Department of Surgical Sciences, Division of Otorhinolaryngology, Turin, Italy.

出版信息

Braz J Otorhinolaryngol. 2022 Nov-Dec;88 Suppl 4(Suppl 4):S33-S43. doi: 10.1016/j.bjorl.2021.06.009. Epub 2021 Jul 30.

DOI:10.1016/j.bjorl.2021.06.009
PMID:34407916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9756059/
Abstract

INTRODUCTION

Partial glossectomy and reconstruction strategy for malignant tongue tumors influences speech and swallowing.

OBJECTIVE

The aim of this retrospective study was to evaluate long-term functional outcomes after partial glossectomy for pT2 mobile tongue carcinomas with a maximum dimension between 2 and 3cm. Different reconstruction strategies (with or without pedicled flap) were compared.

METHODS

Twenty-two patients with at least 12 months followup were included. Clinician-based and self-reported instruments were used to analyze tongue motility, speech intelligibility and articulation, swallowing, and quality of life.

RESULTS

Patients with a higher tongue motility had better articulation and lower dysphagia. Avoiding pedicled flap reconstruction seemed to guarantee lower impairment of speech and swallowing. Worse functional outcomes induced a lower quality of life.

CONCLUSION

Partial glossectomy results in tongue motility impairment and consequently alterations of oral functions. Since the type of reconstruction impacts long-term outcomes, it should be adequately planned before surgery.

摘要

简介

部分舌切除术和恶性舌肿瘤的重建策略会影响言语和吞咽功能。

目的

本回顾性研究的目的是评估最大尺寸为 2 至 3cm 的 pT2 可移动舌癌行部分舌切除术后的长期功能结果。比较了不同的重建策略(带蒂瓣或不带蒂瓣)。

方法

共纳入 22 例至少随访 12 个月的患者。使用基于临床医生和自我报告的工具来分析舌运动、言语清晰度和发音、吞咽和生活质量。

结果

舌运动能力较高的患者发音和吞咽功能更好。避免带蒂瓣重建似乎可以保证言语和吞咽功能受损较小。较差的功能结果导致生活质量降低。

结论

部分舌切除术导致舌运动障碍,进而导致口腔功能改变。由于重建类型会影响长期结果,因此应在手术前进行充分的规划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/2ac177d9175a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/442cb20fda1e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/c1b501e25e4c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/ac754af0b272/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/2c1379076d4f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/2ac177d9175a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/442cb20fda1e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/c1b501e25e4c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/ac754af0b272/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/2c1379076d4f/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1680/9756059/2ac177d9175a/gr5.jpg

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本文引用的文献

1
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2
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Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jan;127(1):24-29. doi: 10.1016/j.oooo.2018.07.007. Epub 2018 Jul 21.
3
Classification of tongue cancer resection and treatment algorithm.
口腔肿瘤治疗后的吞咽功能:一项为期五年的前瞻性研究。
Cancers (Basel). 2023 Sep 1;15(17):4371. doi: 10.3390/cancers15174371.
4
Speech disorders in patients with Tongue squamous cell carcinoma: A longitudinal observational study based on a questionnaire and acoustic analysis.舌鳞状细胞癌患者的言语障碍:基于问卷和声学分析的纵向观察研究。
BMC Oral Health. 2023 Apr 1;23(1):192. doi: 10.1186/s12903-023-02888-1.
5
Effect of Radiotherapy on Functional and Health-Related Quality of Life Outcomes after Jaw Reconstruction.放疗对颌骨重建后功能及健康相关生活质量结局的影响。
Cancers (Basel). 2022 Sep 20;14(19):4557. doi: 10.3390/cancers14194557.
6
Current status and evolution of microsurgical tongue reconstructions, part I.显微外科舌重建的现状与进展,第一部分
Arch Craniofac Surg. 2022 Aug;23(4):139-151. doi: 10.7181/acfs.2022.00654. Epub 2022 Aug 20.
舌癌切除术的分类及治疗算法。
J Surg Oncol. 2018 Apr;117(5):1092-1099. doi: 10.1002/jso.24991. Epub 2018 Feb 12.
4
Grading Dysphagia as a Toxicity of Head and Neck Cancer: Differences in Severity Classification Based on MBS DIGEST and Clinical CTCAE Grades.将吞咽困难分级作为头颈癌的一种毒性反应:基于MBS DIGEST和临床CTCAE分级的严重程度分类差异
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5
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9
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10
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Int J Cancer. 2015 Mar 1;136(5):E359-86. doi: 10.1002/ijc.29210. Epub 2014 Oct 9.