Yagnik Lokesh, Harryanto Hilman, Koay Mei Hui Eleanor, Dessauvagie Ben, Salamonsen Matthew
Department of Respiratory medicine Fiona Stanley Hospital Murdoch WA Australia.
PathWest Laboratory Medicine WA Fiona Stanley Hospital Murdoch WA Australia.
Respirol Case Rep. 2018 Aug 16;6(7):e00359. doi: 10.1002/rcr2.359. eCollection 2018 Oct.
Granular cell tumours (GCT) are uncommon, usually solitary tumours of neural/Schwann cell origin that occur at any site of the body, and typically run an indolent clinical course. Treatment by excision is recommended. Distant or nodal metastases are the only reliable signs of malignancy. We describe the case of a 47-year-old woman with a multi-focal, multi-centric GCT involving the pulmonary and gastrointestinal systems, highlighting the imaging and pathological features and the challenge faced in establishing its malignant potential.
颗粒细胞瘤（GCT）并不常见，通常是起源于神经/施万细胞的孤立性肿瘤，可发生于身体的任何部位，临床病程通常较为缓慢。建议采用手术切除治疗。远处或淋巴结转移是唯一可靠的恶性征象。我们描述了一名47岁女性患有累及肺和胃肠道系统的多灶性、多中心GCT的病例，重点介绍了其影像学和病理学特征以及在确定其恶性潜能方面所面临的挑战。
