Tóth S, Mécs I
Acta Microbiol Hung. 1985;32(4):363-8.
It has been observed that certain amino acids may influence the antiviral activity of different types of human interferon (IFN). The effect may be enhancing or inhibitory. A qualitative survey is provided on all three types of human IFN using 23 different amino acids. A more detailed study was carried out with 10 amino acids which proved to be active towards HuIFN-alpha. Their influences on the synergistic antiviral effects of HuIFN-alpha and HuIFN-gamma were also investigated. The dose-dependence curves of their effects on HuIFN-alpha were established.
据观察，某些氨基酸可能会影响不同类型的人干扰素（IFN）的抗病毒活性。这种影响可能是增强性的或抑制性的。使用23种不同的氨基酸对所有三种类型的人干扰素进行了定性研究。对10种被证明对HuIFN-α有活性的氨基酸进行了更详细的研究。还研究了它们对HuIFN-α和HuIFN-γ协同抗病毒作用的影响。建立了它们对HuIFN-α作用的剂量依赖性曲线。
