Mongolu S
Consultant Physician & Endocrinologist Michael White Centre for Diabetes, Endocrinology and Metabolic Bone Diseases, Brocklehurst Building, Hull Royal Infirmary, Anlaby Road, HU3 2RW.
Acute Med. 2018;17(3):160-163.
The Osmotic demyelination syndrome (ODS) primarily occurs with rapid correction of severe hyponatraemia that has been present for more than two or three days. Some patients are, however at risk and can develop ODS at higher sodium concentration and lower rates of correction. A case of Osmotic demyelination Syndrome which developed despite an 'optimal' rate of correction of serum Sodium with good clinical outcome is described. The risk factors that contribute to development of ODS and strategies to prevent this complication are discussed, along with recommendations on how to manage this condition in hospital inpatients.
渗透性脱髓鞘综合征（ODS）主要发生于严重低钠血症快速纠正时，该低钠血症已持续两三天以上。然而，一些患者有风险，在较高钠浓度和较低纠正率情况下也可发生ODS。本文描述了一例尽管血清钠纠正速度“最佳”但仍发生渗透性脱髓鞘综合征且临床结局良好的病例。文中讨论了导致ODS发生的危险因素、预防该并发症的策略，以及关于如何在住院患者中处理这种情况的建议。
