Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia
Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
Diabetes Care. 2018 Nov;41(11):2306-2315. doi: 10.2337/dc18-0831. Epub 2018 Aug 21.
Cardiovascular disease (CVD) mortality has declined substantially in the U.S. The aims of this study were to examine trends and demographic disparities in mortality due to CVD and CVD subtypes among adults with and without self-reported diabetes.
We used the National Health Interview Survey (NHIS) (1985-2014) with mortality follow-up data through the end of 2015 to estimate nationally representative trends and disparities in major CVD, ischemic heart disease (IHD), stroke, heart failure, and arrhythmia mortality among adults ≥20 years of age by diabetes status.
Over a mean follow-up period of 11.8 years from 1988 to 2015 of 677,051 adults, there were significant decreases in major CVD death (all values <0.05) in adults with and without diabetes except adults 20-54 years of age. Among adults with diabetes, 10-year relative changes in mortality were significant for major CVD (-32.7% [95% CI -37.2, -27.9]), IHD (-40.3% [-44.7, -35.6]), and stroke (-29.2% [-40.0, -16.5]), but not heart failure (-0.5% [-20.7, 24.7]), and arrhythmia (-12.0% [-29.4, 77.5]); the absolute decrease of major CVD among adults with diabetes was higher than among adults without diabetes ( < 0.001). Men with diabetes had larger decreases in CVD death than women with diabetes ( < 0.001).
Major CVD mortality in adults with diabetes has declined, especially in men. Large reductions were observed for IHD and stroke mortality, although heart failure and arrhythmia deaths did not change. All race and education groups benefitted to a similar degree, but significant gaps remained across groups.
美国心血管疾病(CVD)死亡率已大幅下降。本研究旨在探讨患有和不患有自我报告糖尿病的成年人中 CVD 和 CVD 亚型死亡率的趋势和人口统计学差异。
我们使用国家健康访谈调查(NHIS)(1985-2014 年),并通过 2015 年底的死亡率随访数据,根据糖尿病状况,估计≥20 岁成年人中主要 CVD、缺血性心脏病(IHD)、中风、心力衰竭和心律失常死亡率的全国代表性趋势和差异。
在 1988 年至 2015 年的 677,051 名成年人平均随访 11.8 年期间,患有和不患有糖尿病的成年人中,主要 CVD 死亡人数均显著下降(所有 值<0.05),除外 20-54 岁的成年人。在患有糖尿病的成年人中,10 年相对死亡率变化在主要 CVD(-32.7% [95%CI-37.2,-27.9])、IHD(-40.3% [-44.7,-35.6])和中风(-29.2% [-40.0,-16.5])方面具有显著意义,但心力衰竭(-0.5% [-20.7,24.7])和心律失常(-12.0% [-29.4,77.5])则没有显著意义;与不患有糖尿病的成年人相比,患有糖尿病的成年人的主要 CVD 绝对减少量更高(<0.001)。患有糖尿病的男性的 CVD 死亡率下降幅度大于女性(<0.001)。
患有糖尿病的成年人的主要 CVD 死亡率已下降,尤其是男性。尽管心力衰竭和心律失常死亡没有变化,但 IHD 和中风死亡率的降幅较大。所有种族和教育群体都受益程度相似,但各群体之间仍存在显著差距。