van Paridon P A, de Kruijff B, Ouwerkerk R, Wirtz K W
Biochim Biophys Acta. 1986 Jun 11;877(1):216-9. doi: 10.1016/0005-2760(86)90137-2.
The charge state of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate was determined as a function of pH by way of 31P-NMR spectroscopy. The pK values for the first protonation of the phosphomonoester residues in phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate were found to be 6.2 and 6.6, respectively, for the 4-phosphate moiety, and 7.7 for the 5-phosphate moiety.
通过31P-核磁共振光谱法测定了磷脂酰肌醇4-磷酸和磷脂酰肌醇4,5-二磷酸的电荷状态与pH的函数关系。发现磷脂酰肌醇4-磷酸和磷脂酰肌醇4,5-二磷酸中磷酸单酯残基第一次质子化的pK值，对于4-磷酸部分分别为6.2和6.6，对于5-磷酸部分为7.7。
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