Department of Chemistry , Shanghai Jiao Tong University , 800 Dongchuan Road , Shanghai 200240 , People's Republic of China.
Org Lett. 2018 Sep 7;20(17):5264-5267. doi: 10.1021/acs.orglett.8b02208. Epub 2018 Aug 22.
Alkyl spC-H bonds of cycloalkanes and functional branch/linear alkanes have been successfully brominated with KBr using air or O as an oxidant at room temperature to 40 °C. The reactions are carried out in the presence of catalytic NaNO in 37% HCl (aq)/solvent under visible light, combining aerobic oxidations and photochemical radical processes. For various alkane substrates, CFCHOH, CHCl, or CHCl is employed as an organic solvent, respectively, to enhance the efficiency of bromination.
在可见光照射下，在 37%盐酸（aq）/溶剂中，以催化量的 NaNO 为催化剂，使用空气或 O 作为氧化剂，在室温至 40°C 下成功地将环烷烃和功能支链/线性烷烃的烷基 spC-H 键溴化。该反应是在有氧氧化和光化学自由基过程的共同作用下进行的。对于各种烷烃底物，分别使用 CFCHOH、CHCl 或 CHCl 作为有机溶剂，以提高溴化效率。
