Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Org Lett. 2021 May 21;23(10):4057-4061. doi: 10.1021/acs.orglett.1c01303. Epub 2021 May 6.
A site-specific oxidation of (sp)C-C(sp) and (sp)C-H bonds in aryl alkanes by the use of NaNO/HCl was explored. The method is chemical-oxidant-free, transition-metal-free, uses water as the solvent, and proceeds under mild conditions, making it valuable and attractive to synthetic organic chemistry.
研究了使用 NaNO/HCl 对芳基烷烃中的 (sp)C-C(sp) 和 (sp)C-H 键进行的位置特异性氧化。该方法无化学氧化剂、无过渡金属，使用水作为溶剂，在温和条件下进行，因此对有机合成化学具有重要价值和吸引力。
