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Glial cell line-derived neurotrophic factor as a treatment after spinal cord injury.

作者信息

Ortmann Stephen D, Hellenbrand Daniel J

机构信息

Department of Neurological Surgery, University of Wisconsin, Madison, WI, USA.

出版信息

Neural Regen Res. 2018 Oct;13(10):1733-1734. doi: 10.4103/1673-5374.238610.

DOI:10.4103/1673-5374.238610
PMID:30136685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6128059/
Abstract
摘要

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Spinal cord protection via alpha-2 agonist-mediated increase in glial cell-line-derived neurotrophic factor.通过 α-2 激动剂介导增加胶质细胞源性神经营养因子来保护脊髓。
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Glial cell line-derived neurotrophic factor enhances survival and growth of prenatal and postnatal spinal cord transplants.胶质细胞系源性神经营养因子可提高产前和产后脊髓移植的存活率并促进其生长。
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Spinal glial cell line-derived neurotrophic factor infusion reverses reduction of Kv4.1-mediated A-type potassium currents of injured myelinated primary afferent neurons in a neuropathic pain model.脊髓胶质细胞系衍生神经营养因子输注逆转神经病理性疼痛模型中损伤有髓传入神经元 Kv4.1 介导的 A 型钾电流减少。
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[TRANSPLANTATION OF NEURAL STEM CELLS INDUCED BY ALL-TRANS- RETINOIC ACID COMBINED WITH GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR AND CHONDROITINASE ABC FOR REPAIRING SPINAL CORD INJURY OF RATS].全反式维甲酸联合胶质细胞源性神经营养因子及软骨素酶ABC诱导神经干细胞移植修复大鼠脊髓损伤
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本文引用的文献

1
The Effects of Glial Cell Line-Derived Neurotrophic Factor after Spinal Cord Injury.脊髓损伤后胶质细胞源性神经营养因子的作用。
J Neurotrauma. 2017 Dec 15;34(24):3311-3325. doi: 10.1089/neu.2017.5175. Epub 2017 Oct 16.
2
The GDNF-GFRα1 complex promotes the development of hippocampal dendritic arbors and spines via NCAM.胶质细胞源性神经营养因子-胶质细胞源性神经营养因子受体α1复合物通过神经细胞黏附分子促进海马树突棘和树突分支的发育。
Development. 2016 Nov 15;143(22):4224-4235. doi: 10.1242/dev.140350. Epub 2016 Oct 5.
3
Sustained release of neurotrophin-3 via calcium phosphate-coated sutures promotes axonal regeneration after spinal cord injury.
用于脊髓损伤治疗的生物材料介导因子递送
Biomedicines. 2022 Jul 12;10(7):1673. doi: 10.3390/biomedicines10071673.
4
Minocycline Enhance the Restorative Ability of Olfactory Ensheathing Cells by the Upregulation of BDNF and GDNF Expression After Spinal Cord Injury.米诺环素通过上调脊髓损伤后脑源性神经营养因子(BDNF)和胶质细胞源性神经营养因子(GDNF)的表达增强嗅鞘细胞的修复能力。
Basic Clin Neurosci. 2021 Nov-Dec;12(6):777-788. doi: 10.32598/bcn.2021.1727.1. Epub 2021 Nov 1.
5
Agathisflavone as a Single Therapy or in Association With Mesenchymal Stem Cells Improves Tissue Repair in a Spinal Cord Injury Model in Rats.阿盖黄酮单独治疗或与间充质干细胞联合使用可改善大鼠脊髓损伤模型中的组织修复。
Front Pharmacol. 2022 Apr 5;13:858190. doi: 10.3389/fphar.2022.858190. eCollection 2022.
6
Eriodictyol corrects functional recovery and myelin loss in SCI rats.圣草酚可改善脊髓损伤大鼠的功能恢复并减轻髓鞘损失。
Transl Neurosci. 2020 Dec 31;11(1):439-446. doi: 10.1515/tnsci-2020-0128. eCollection 2020.
7
Functional recovery after peripheral nerve injury via sustained growth factor delivery from mineral-coated microparticles.通过从矿物涂层微粒持续递送生长因子实现周围神经损伤后的功能恢复。
Neural Regen Res. 2021 May;16(5):871-877. doi: 10.4103/1673-5374.297786.
8
Differential expression of glial cell line-derived neurotrophic factor splice variants in the mouse brain.胶质细胞源性神经营养因子剪接变体在小鼠大脑中的差异表达。
Neural Regen Res. 2020 Feb;15(2):270-276. doi: 10.4103/1673-5374.265561.
9
CNB-001 reduces paraplegia in rabbits following spinal cord ischemia.CNB-001可降低兔脊髓缺血后的截瘫发生率。
Neural Regen Res. 2019 Dec;14(12):2192-2198. doi: 10.4103/1673-5374.262598.
10
Beyond Trophic Factors: Exploiting the Intrinsic Regenerative Properties of Adult Neurons.超越营养因子:利用成年神经元的内在再生特性
Front Cell Neurosci. 2019 Apr 5;13:128. doi: 10.3389/fncel.2019.00128. eCollection 2019.
通过磷酸钙包被缝线持续释放神经营养因子-3可促进脊髓损伤后的轴突再生。
J Neurosci Res. 2016 Jul;94(7):645-52. doi: 10.1002/jnr.23730. Epub 2016 Mar 26.
4
Multilayered Inorganic Microparticles for Tunable Dual Growth Factor Delivery.用于可调谐双生长因子递送的多层无机微粒
Adv Funct Mater. 2014 May 28;24(20):3082-3093. doi: 10.1002/adfm.201302859.
5
Spinal cord injury facts and figures at a glance.脊髓损伤事实与数据概览。
J Spinal Cord Med. 2013 Jan;36(1):1-2. doi: 10.1179/1079026813Z.000000000136.
6
GDNF and GFRalpha: a versatile molecular complex for developing neurons.胶质细胞源性神经营养因子(GDNF)与胶质细胞源性神经营养因子受体α(GFRalpha):一种促进神经元发育的多功能分子复合物。
Trends Neurosci. 2008 Aug;31(8):384-91. doi: 10.1016/j.tins.2008.05.003. Epub 2008 Jul 1.
7
Neurotrophic factors expressed in both cortex and spinal cord induce axonal plasticity after spinal cord injury.在皮层和脊髓中表达的神经营养因子可诱导脊髓损伤后轴突可塑性。
J Neurosci Res. 2003 Oct 15;74(2):221-6. doi: 10.1002/jnr.10718.
8
The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands.神经细胞黏附分子NCAM是胶质细胞源性神经营养因子(GDNF)家族配体的一种替代性信号受体。
Cell. 2003 Jun 27;113(7):867-79. doi: 10.1016/s0092-8674(03)00435-5.
9
The GDNF family: signalling, biological functions and therapeutic value.胶质细胞源性神经营养因子家族:信号传导、生物学功能及治疗价值
Nat Rev Neurosci. 2002 May;3(5):383-94. doi: 10.1038/nrn812.
10
Released GFRalpha1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts.释放的GFRalpha1通过一种将c-Ret招募到脂筏的新机制增强下游信号传导、神经元存活和分化。
Neuron. 2001 Jan;29(1):171-84. doi: 10.1016/s0896-6273(01)00188-x.