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[内脏大神经对胃运动活动的刺激机制]

[Mechanism of stimulation of the motor activity of the stomach by the greater splanchnic nerve].

作者信息

Smironov V M, Klevtsov V A, Lychkov A A, Popova L M, Smirnov N A

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 May;72(5):650-5.

PMID:3013699
Abstract

The activating effect of the splanchnic nerve on motor activity of the gastro-intestinal tract could not be eliminated either with bilateral vagotomy or separate or joint administration of ornid and benzohexonium, but could be well prevented with atropin blockade of the vegetative ganglia M-serotoninergic receptors as well as diprazin blockade of the smooth muscle D-serotoninergic receptors. The data obtained reveal non-cholinergic and non-adrenergic fibers in the thoracic portion of the major splanchnic nerve which exert obvious activating effect on the stomach contractile function, serotonin being their transmitter.

摘要

内脏神经对胃肠道运动活动的激活作用,无论是双侧迷走神经切断术,还是单独或联合使用奥尼德和苯六甲铵,都无法消除,但通过阿托品阻断植物神经节M - 5羟色胺能受体以及地普雷嗪阻断平滑肌D - 5羟色胺能受体,可以很好地预防这种作用。所获得的数据揭示,在内脏大神经胸部段存在非胆碱能和非肾上腺素能纤维,它们对胃的收缩功能具有明显的激活作用,5羟色胺是其递质。

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