Alkhybari Essam M, McEntee Mark F, Brennan Patrick C, Willowson Kathy P, Hogg Peter, Kench Peter L
The Discipline of Medical Radiation Sciences, Faculty of Health Sciences, The University of Sydney, NSW 2006 Australia.
Department of Radiology and Medical Imaging, Faculty of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Al Kharj, Saudi Arabia.
Radiat Prot Dosimetry. 2018 Dec 1;182(4):532-545. doi: 10.1093/rpd/ncy113.
The aim of this systematic review is to investigate the national diagnostic reference level (NDRL) methods for positron emission tomography/computed tomography (PET/CT) and single photon emission tomography/computed tomography (SPECT/CT) procedures. A search strategy was based on the preferred, reporting items for systematic review and meta-analysis (PRISMA). Relevant articles retrieved from Medline, Scopus, Web of Science, Embase, Cinahl, and Google Scholar published up to October 2017. The search yielded 1057 articles. Fourteen articles were included in the review after a screening process. Relevant information from the selected articles were summarised and analysed. Discrepancies were found between the methodologies utilised to establish and report both PET/CT and SPECT/CT NDRLs, e.g. patient sampling and administered activity. Further research should focus on reporting more NDRLs for hybrid PET/CT and SPECT/CT examinations, and establish a robust NDRL standard for the CT portion associated with PET/CT and SPECT/CT examinations. This review provides updated NDRL reommndations to deliver more comparable international radation doses for administered activity and CT dose across PET/CT and SPECT/CT clinics.
本系统评价的目的是研究正电子发射断层扫描/计算机断层扫描（PET/CT）和单光子发射断层扫描/计算机断层扫描（SPECT/CT）检查的国家诊断参考水平（NDRL）方法。检索策略基于系统评价和荟萃分析的首选报告项目（PRISMA）。从Medline、Scopus、科学网、Embase、护理学与健康领域数据库（Cinahl）以及谷歌学术中检索截至2017年10月发表的相关文章。检索共获得1057篇文章。经过筛选过程，14篇文章被纳入本评价。对所选文章的相关信息进行了总结和分析。发现用于建立和报告PET/CT和SPECT/CT NDRL的方法之间存在差异，例如患者抽样和给药活度。进一步的研究应侧重于报告更多混合PET/CT和SPECT/CT检查的NDRL，并为与PET/CT和SPECT/CT检查相关的CT部分建立稳健的NDRL标准。本评价提供了最新的NDRL建议，以便在PET/CT和SPECT/CT诊所提供更具可比性的给药活度和CT剂量的国际辐射剂量。
