Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
Environ Geochem Health. 2019 Apr;41(2):803-816. doi: 10.1007/s10653-018-0175-z. Epub 2018 Aug 23.
The health effects of living in proximity to Superfund sites with ongoing remediation were evaluated for residents of two contiguous Montana counties, Deer Lodge and Silver Bow. Deer Lodge and Silver Bow are home to the Anaconda Smelter and Silver Bow Creek/Butte Area Superfund sites, respectively. Established by the Environmental Protection Agency in 1983, both sites have had ongoing remediation for decades. Employing county level death certificate data obtained from the Centers for Disease Control and Prevention WONDER site, sex and age-adjusted standardized mortality ratios (SMRs) for composite targeted causes of death were calculated using observed versus expected mortality for both counties, and compared to the expected mortality from the remaining Montana counties. Cancers, cerebro- and cardiovascular diseases (CCVD), and organ failure were elevated for the two counties during the study period, 2000-2016, with SMRs of 1.19 (95% CI 1.10, 1.29); 1.36 (95% CI 1.29, 1.43); and 1.24 (95% CI 1.10, 1.38), respectively. Neurological conditions were not elevated for the two counties (SMR = 1.01; 95% CI 0.89, 1.14). Time trend analyses performed using Cox regression models indicate that deaths from cancers (HR = 0.97; p = 0.0004), CCVDs (HR = 0.95; p ≤ 0.0001), and neurological conditions (HR = 0.97; p = 0.01) decreased over the study period. While the ecological approach applied limits the interpretation of our results, our study suggests that while mortality is elevated, it is also decreasing over time for these two Superfund sites.
对毗邻蒙大拿州两个县——迪尔洛奇县和西尔弗博县——的居民进行了居住在超级基金场地附近并正在进行补救的健康影响评估。迪尔洛奇县和西尔弗博县分别是安纳康达冶炼厂和西尔弗博溪/比尤特地区超级基金场地的所在地。这两个场地均由美国环境保护署于 1983 年设立,且数十年来一直在进行补救。本研究利用从疾病控制与预防中心 WONDER 网站获取的县级死亡证明数据,通过比较两县的实际死亡率与预期死亡率,计算了复合目标死因的性别和年龄调整标准化死亡率(SMR)。将两个县在 2000 年至 2016 年研究期间的癌症、脑心血管疾病(CCVD)和器官衰竭的 SMR 与蒙大拿州其余县的预期死亡率进行了比较。结果显示,在此期间,这两个县的癌症、CCVD 和器官衰竭的 SMR 分别为 1.19(95%CI 1.10,1.29)、1.36(95%CI 1.29,1.43)和 1.24(95%CI 1.10,1.38),均有所升高。然而,这两个县的神经疾病并没有升高(SMR=1.01;95%CI 0.89,1.14)。使用 Cox 回归模型进行的时间趋势分析表明,癌症(HR=0.97;p=0.0004)、CCVD(HR=0.95;p≤0.0001)和神经疾病(HR=0.97;p=0.01)的死亡率在研究期间呈下降趋势。虽然应用的生态方法限制了对我们研究结果的解释,但我们的研究表明,尽管死亡率有所升高,但随着时间的推移,这两个超级基金场地的死亡率也在下降。