Hailer M Katie, Peck Christopher P, Calhoun Michael W, West Robert F, James Kyle J, Siciliano Steven D
Department of Chemistry, Montana Tech, Butte, MT USA.
Statistical Consulting and Research Services, Montana State University, Bozeman, MT USA.
Environ Toxicol Pharmacol. 2017 Sep;54:112-119. doi: 10.1016/j.etap.2017.06.001. Epub 2017 Jun 27.
Butte, Montana is part of the largest superfund site in the continental United States. Open-pit mining continues in close proximity to Butte's urban population. This study seeks to establish baseline metal concentrations in the hair and blood of individuals living in Butte, MT and possible routes of exposure. Volunteers from Butte (n=116) and Bozeman (n=86) were recruited to submit hair and blood samples and asked to complete a lifestyle survey. Elemental analysis of hair and blood samples was performed by ICP-MS. Three air monitors were stationed in Butte to collect particulate and filters were analyzed by ICP-MS. Soil samples from the yards of Butte volunteers were quantified by ICP-MS. Hair analysis revealed concentrations of Al, As, Cd, Cu, Mn, Mo, and U to be statistically elevated in Butte's population. Blood analysis revealed that the concentration of As was also statistically elevated in the Butte population. Multiple regression analysis was performed for the elements As, Cu, and Mn for hair and blood samples. Soil samples revealed detectable levels of As, Pb, Cu, Mn, and Cd, with As and Cu levels being higher than expected in some of the samples. Air sampling revealed consistently elevated As and Mn levels in the larger particulate sampled as compared to average U.S. ambient air data.
蒙大拿州的比尤特是美国大陆最大的超级基金污染场地的一部分。露天采矿在靠近比尤特城市人口的地方持续进行。本研究旨在确定居住在蒙大拿州比尤特的个人头发和血液中的金属基线浓度以及可能的接触途径。招募了来自比尤特（n = 116）和博兹曼（n = 86）的志愿者提交头发和血液样本，并要求他们完成一份生活方式调查问卷。通过电感耦合等离子体质谱法（ICP-MS）对头发和血液样本进行元素分析。在比尤特设置了三个空气监测器来收集颗粒物，并用ICP-MS对过滤器进行分析。对比尤特志愿者庭院的土壤样本用ICP-MS进行定量分析。头发分析显示，比尤特居民中铝、砷、镉、铜、锰、钼和铀的浓度在统计学上有所升高。血液分析显示，比尤特居民中砷的浓度在统计学上也有所升高。对头发和血液样本中的砷、铜和锰元素进行了多元回归分析。土壤样本显示可检测到砷、铅、铜、锰和镉的含量，其中一些样本中的砷和铜含量高于预期。空气采样显示，与美国平均环境空气数据相比，在采集的较大颗粒物中，砷和锰的含量持续升高。
