Islam M S, Gafur M A, Mahmud A A, Mahiuddin M, Khan S A, Reza E, Rahman M S, Mahmud M, Karim M R, Hoque M M, Salam M A, Khan M H
Dr Md Shofiqul Islam, Senior Consultant (Surgery), 250 Bedded General Hospital, Tangail, Bangladesh.
Mymensingh Med J. 2018 Jul;27(3):513-519.
Enterocutaneous fistulae are a major catastrophe to the patients and surgeons and it still has high incidence of morbidity and mortality and their management remains a big challenge. Enterocutaneous fistula presents the surgeon with challenges of metabolic disorders and extensive sepsis. Total management of an intestinal fistula requires skill in nutritional support, stoma therapy, elimination of sepsis, well timed and well carried out surgery. Postoperative enterocutaneous fistulae account for approximately 80% of enterocutaneous fistulae. The majority of the intestinal fistula (75-85%) is iatrogenic occurring in the postoperative period following anastomotic dehiscence. They arise following emergency abdominal surgery for intestinal obstruction, inflammatory bowel disease or cancers. Protein calorie malnutrition alters the patients immune response, inflammatory reactions and tissue regenerations, all of which are essential for wound repair. The present study is an effort to highlight the incidence of enterocutaneous fistula after emergency and elective resection and anastomosis of gut with discussion over recent trends and developments in its management and compare with other studies. Objectives of the study are to determine the various clinicopathological features and management protocol of enterocutaneous fistula. There are recent advances in nutritional support. This descriptive type of cross-sectional study was carried out in the Department of Surgery, Mymensingh Medical College and Hospital, Mymensingh, Bangladesh from October 2010 to September 2011. Total 42 cases of enterocutaneous fistulae were selected purposively. Enterocutaneous fistulae are more common in patients of low economic condition. Enterocutaneous fistulae are more common after emergency abdominal surgery. Spontaneous closure occurred in 17(40.48%) cases and surgery needed in 25(59.52%) cases. Of them 20(80.00%) were healed and 5(20.00%) were expired. In spite of improvement in the management protocol of enterocutaneous fistula, there is still high unacceptable morbidity and mortality rate. Total parenteral nutrition (TPN) is not available and very costly, and health care facilities are also limited in our country. Patients with enterocutaneous fistula require fluid, electrolytes and nutritional support. Anaemia, dehydration, electrolytes imbalance should be corrected prior to abdominal surgery if possible. Surgical treatment for enterocutaneous fistula should be performed only after failure of conservative treatment of more than 12 weeks.
肠外瘘对患者和外科医生来说都是一场重大灾难,其发病率和死亡率仍然很高,对其进行管理仍然是一个巨大的挑战。肠外瘘给外科医生带来了代谢紊乱和严重脓毒症的挑战。肠瘘的全面管理需要营养支持、造口治疗、消除脓毒症、适时且妥善实施手术等技能。术后肠外瘘约占肠外瘘的80%。大多数肠瘘(75%-85%)是医源性的,发生在吻合口裂开后的术后阶段。它们发生在因肠梗阻、炎症性肠病或癌症而进行的急诊腹部手术后。蛋白质热量营养不良会改变患者的免疫反应、炎症反应和组织再生,而这些对于伤口修复都是必不可少的。本研究旨在强调急诊和择期肠道切除吻合术后肠外瘘的发生率,并讨论其管理的最新趋势和进展,并与其他研究进行比较。该研究的目的是确定肠外瘘的各种临床病理特征和管理方案。营养支持方面有了新进展。这项描述性横断面研究于2010年10月至2011年9月在孟加拉国迈门辛医学院和医院外科进行。共故意选取了42例肠外瘘病例。肠外瘘在经济条件差的患者中更为常见。肠外瘘在急诊腹部手术后更为常见。17例(40.48%)病例实现了自发闭合,25例(59.52%)病例需要手术。其中20例(80.00%)治愈,5例(20.00%)死亡。尽管肠外瘘的管理方案有所改进,但发病率和死亡率仍然高得令人难以接受。全胃肠外营养(TPN)无法获得且成本非常高,而且我国的医疗设施也有限。肠外瘘患者需要液体、电解质和营养支持。如有可能,在腹部手术前应纠正贫血、脱水和电解质失衡。肠外瘘的手术治疗应仅在保守治疗超过12周失败后进行。