Cheng Shi-lei, Wang Hu, Ma Xiao, Zhang Jing-xiao, Liu Yu-fang, Cai Hui-xia, Liu Pei-yun, Ma Jun-ying, He Duo-long, Wu Xian-hong, Han Xiu-min, Wang Yong-shun, Liu Hai-qing, Zhao Yan-mei, Liu Ba-rui, Zeng Cheng, Wang Wei, Du Rui, Lei Wen, Su Guo-ming, Zhou Ben-jia, Song Cheng-xi, Wang Yuan-jia
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2016 Dec;34(6):547-51.
To investigate the prevalence of echinococcosis in Yushu Prefecture of Qinghai Province in 2012.
Two to three towns were selected in each of Chengduo, Nangqian, Qu malai, Yushu, Zaduo and Zhiduo Counties from June to August in 2012. Ultrasound examination was conducted for residents aged over 1 year, and ELISA was performed to detect serum antibody against Echinococcus. Visceral dissection was performed to detect hydatid infection in rodents and livestock. ELISA was used to detect Echinococcus antigen in collected dog feces.
A total of 7 025 residents received ultrasound examination, of whom 319 showed hydatid cysts with a morbidity rate of 4.54%. ELISA showed a serum antibody positive rate of 16.38% （457/2 790）. The mobidity of hydatid disease was highest in Chengduo County （7.41%, 181/2 444）, and the rate of serum antibody was highest in Yushu County （23.18%, 127/548）. The morbidity and serum antibody in males were 3.91% （118/3 018） and 13.93% （172/1 235） respectively, and those in females were 5.02% （201/4 007） and 18.33% （285/1 555）. In terms of age distribution, the morbidity was relatively higher in residents of 60- （8.39%, 38/453） and 40- years （6.61%, 67/1 014）; and the rate of serum antibody was highest in residents over 70 years （33.93%, 19/56）. In terms of occupation, the morbidity was relatively higher in herdsmen （5.28%, 252/4 777）, Herdsmen-peasants （6.52%, 24/368）, and religious workers（3.37%, 11/326）, while the rate of serum antibody was relatively higher in children（24%, 6/25）, religious workers （18.79%, 31/165） and herdsmen（18.34%, 328/1 788）. In terms of education level, the morbidity and the rate of serum antibody were both highest in the uneducated（5.04%, 41/4 779; 18.34%, 359/1 958, respectively）. In terms of residential pattern, the morbidity and the rate of serum antibody were both highest in those who were settled in winter and nomadic in summer （8.25%, 227/2 753; 19.48%, 158/811, respectively）. There were significant differences in the morbidity and the rate of serum antibody in aspects of residential region, sex, age, occupation, education level and residential pattern (P<0.05 or P<0.01). In 872 rodents detected, the Echinococcus hydatid rate was 0.46% （4/872）, while in 809 cattle and sheep detected, the Echinococcus hydatid rate was 10.14% （82/809）. The fecal antigen positive rate in 838 samples of dog feces was 10.74%（90/838）.
It shows a high morbidity of hydatid diesease and serum antibody positive rate in residents, a high Echinococcus hydatid rate in cattle and sheep, and a high fecal antigen positive rate in dogs in Yushu Prefecture.
调查2012年青海省玉树州棘球蚴病的患病率。
2012年6至8月，在称多、囊谦、曲麻莱、玉树、杂多和治多县各选取两到三个乡镇。对1岁以上居民进行超声检查，采用酶联免疫吸附测定（ELISA）检测血清棘球蚴抗体。进行内脏解剖以检测啮齿动物和家畜中的包虫感染情况。采用ELISA检测所采集犬粪便中的棘球蚴抗原。
共有7025名居民接受了超声检查，其中319人显示有包虫囊肿，患病率为4.54%。ELISA显示血清抗体阳性率为16.38%（457/2790）。称多县包虫病患病率最高（7.41%，181/2444），玉树县血清抗体阳性率最高（23.18%，127/548）。男性的患病率和血清抗体阳性率分别为3.91%（118/3018）和13.93%（172/1235），女性分别为5.02%（201/4007）和18.33%（285/1555）。在年龄分布方面，60岁及以上居民（8.39%，38/453）和40岁及以上居民（6.61%，67/1014）的患病率相对较高；70岁以上居民的血清抗体阳性率最高（33.93%，19/56）。在职业方面，牧民（5.28%，252/4777）、半农半牧者（6.52%，24/368）和宗教工作人员（3.37%，11/326）的患病率相对较高，而儿童（24%，6/25）、宗教工作人员（18.79%，31/165）和牧民（18.34%，328/1788）的血清抗体阳性率相对较高。在教育程度方面，未受过教育者的患病率和血清抗体阳性率均最高（分别为5.04%，41/4779；18.34%于359/1958）。在居住方式方面，冬春定居夏秋游牧者的患病率和血清抗体阳性率均最高（分别为8.25%，227/2753；19.48%，158/811）。在居住地区、性别、年龄、职业、教育程度和居住方式等方面，患病率和血清抗体阳性率存在显著差异（P<0.05或P<0.01）。在检测的872只啮齿动物中，包虫感染率为0.46%（4/872），而在检测的809头牛和羊中，包虫感染率为10.14%（82/809）。838份犬粪便样本中粪便抗原阳性率为10.74%（90/838）。
玉树州居民包虫病患病率和血清抗体阳性率较高，牛羊包虫感染率较高，犬粪便抗原阳性率较高。
