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孕期TORCH病原体抗体检测

[Detection of antibodies against TORCH agents during pregnancy].

作者信息

Ustaçelebi S, Köksal I, Cantürk H, Saify S J, Ersöz D, Sellioğlu B

出版信息

Mikrobiyol Bul. 1986 Jan;20(1):1-8.

PMID:3014280
Abstract

The antibody levels against TORCH agents in sera samples from pregnant women who admitted to Hacettepe Medical Faculty Hospital Obstetrics and Gynecology Department were tested. The measurements of IgG antibodies by ELISA against Toxoplasma gondii in 301 sera was given 47.8% sero-positivity. Rubella ELISA-IgG test performed for 226 sera given 89.8% seropositive value. 128 sera were also tested for the presence of Cytomegalovirus (CMV) IgG antibodies and 87.5% seropositivity is found. Complement fixation test is employed for the detection of Herpes simplex virus type 1 (HSV) antibodies in 65 sera samples and 87.5% of sera tested were given positive result in various titers. These results are discussed in terms of seronegativity of this population, sensitivity of ELISA test and the distribution of antibody levels.

摘要

对入住哈杰泰佩医科大学医院妇产科的孕妇血清样本中针对TORCH病原体的抗体水平进行了检测。通过ELISA法对301份血清样本检测弓形虫IgG抗体,血清阳性率为47.8%。对226份血清样本进行风疹ELISA-IgG检测,血清阳性率为89.8%。还对128份血清样本检测巨细胞病毒(CMV)IgG抗体的存在情况,血清阳性率为87.5%。采用补体结合试验检测65份血清样本中1型单纯疱疹病毒(HSV)抗体,87.5%的检测血清在不同滴度下呈阳性结果。从该人群的血清阴性、ELISA检测的敏感性以及抗体水平分布方面对这些结果进行了讨论。

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