沙特孕妇中的TORCH病原体
TORCH agents in pregnant Saudi women.
作者信息
Ghazi Hani O, Telmesani Abdulwahab M, Mahomed Mahomed F
机构信息
Department of Microbiology, Faculty of Medicine and Medical Sciences, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia.
出版信息
Med Princ Pract. 2002 Oct-Dec;11(4):180-2. doi: 10.1159/000065813.
OBJECTIVE
To determine the seroprevalence rates of IgG to common TORCH agents in pregnant Saudi women using indirect enzyme-linked immunosorbent assay.
SUBJECTS AND METHODS
A total of 926 samples of sera were tested for antibodies to TORCH agents known to cause serious congenital infections: Toxoplasma gondii, rubella, cytomegalovirus (CMV), herpes simplex viruses (HSV-1 and HSV-2), varicella zoster virus (VZV) and human immunodeficiency virus (HIV-1 and HIV-2).
RESULTS
Toxoplasma IgG antibodies were detected in 35.6%, CMV total IgG antibodies were found in 92.1%, rubella IgG antibodies in 93.3%, HSV-1 IgG antibodies in 90.9%, HSV-2 IgG in 27.1%, and VZV IgG antibodies in 74.4%. A 0% seroprevalence rate for HIV-1 and -2 was found.
CONCLUSION
Pregnant Saudi women commonly have IgG antibodies to rubella, CMV, HSV-1 and -2, VZV, and T. gondii. Serological evidence of HIV infection was not observed.
目的
采用间接酶联免疫吸附测定法确定沙特孕妇中针对常见TORCH病原体的IgG血清阳性率。
对象与方法
共检测了926份血清样本，以检测针对已知会导致严重先天性感染的TORCH病原体的抗体：弓形虫、风疹、巨细胞病毒（CMV）、单纯疱疹病毒（HSV-1和HSV-2）、水痘带状疱疹病毒（VZV）和人类免疫缺陷病毒（HIV-1和HIV-2）。
结果
检测到弓形虫IgG抗体的比例为35.6%，CMV总IgG抗体为92.1%，风疹IgG抗体为93.3%，HSV-1 IgG抗体为90.9%，HSV-2 IgG为27.1%，VZV IgG抗体为74.4%。HIV-1和-2的血清阳性率为0%。
结论
沙特孕妇普遍存在针对风疹、CMV、HSV-1和-2、VZV及弓形虫的IgG抗体。未观察到HIV感染的血清学证据。
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