University of Florida, Department of Pediatrics, Division of Neonatology, Gainesville, FL, USA.
University of Florida, Department of Pediatrics, Division of Neonatology, Gainesville, FL, USA.
Semin Fetal Neonatal Med. 2018 Dec;23(6):406-410. doi: 10.1016/j.siny.2018.08.003. Epub 2018 Aug 17.
Enteral feeding and composition play a chief role in the prevention and treatment of necrotizing enterocolitis (NEC). In the face of decades of research on this fatal disease, the exact mechanism of disease is still poorly understood. There is established evidence that providing mother's own breast milk and standardization of feeding regimens leads to a decreased risk for NEC. More recent studies have focused on the provision of donor human milk or an exclusive human milk diet in the endeavor to prevent NEC while still maintaining adequate nutrition to the premature infant. There is growing literature on the provision of specific human milk components and its effect on the incidence of NEC.
肠内喂养和组成在坏死性小肠结肠炎(NEC)的预防和治疗中起着主要作用。面对几十年来对这种致命疾病的研究,疾病的确切机制仍知之甚少。有确凿的证据表明,提供母亲自己的母乳和喂养方案的标准化可降低 NEC 的风险。最近的研究集中在提供捐赠人乳或纯人乳饮食,以努力在预防 NEC 的同时为早产儿提供足够的营养。关于提供特定的人乳成分及其对 NEC 发生率的影响的文献越来越多。