Department of Surgery, Surgical Oncology and Science, Sapporo Medical University, South 1, West 16, Chuo-ku, Sapporo, 060-8543, Japan.
JR Sapporo Hospital, North 3, East 1, Chuo-ku, Sapporo, 060-0033, Japan.
Int J Clin Oncol. 2019 Feb;24(2):189-195. doi: 10.1007/s10147-018-1340-1. Epub 2018 Aug 24.
The current status and adoption of cancer-related clinical practice guidelines in Japan has not been elucidated yet. The purpose of this study was to propose roles and suggestions to develop future cancer-related clinical guidelines.
A questionnaire consisting of four domains with a total of 17 questions was developed. We distributed the questionnaire to 28 specific academic organizations in Japan which have developed any cancer-related clinical practice guidelines and which were funded by the Ministry of Health, Labor, and Welfare.
Most organizations have investigated nationwide dissemination and adoption of clinical practice guidelines. The rate of adoption in clinical practice was estimated at approximately ≥ 70%. However, organizations with smaller budgets reported surveying approximately 60% of the time, whereas the ones with larger budgets reported approximately 100% success in surveying about their guidelines. The presidents of the organizations agreed that a new organization operated directly by the national government was necessary.
In Japan, to develop cancer-related clinical practice guidelines, a study of clinical validation is necessary. Sufficient funds must be available to support the project to maintain and revise the guidelines. Furthermore, legal and ethical issues should be solved before establishing any registry system.
目前在日本，癌症相关临床实践指南的现状和采用情况尚未阐明。本研究的目的是提出作用和建议，以制定未来的癌症相关临床指南。
我们制定了一份包含四个领域共 17 个问题的问卷，并分发给日本 28 个特定的学术组织。这些组织都制定过癌症相关的临床实践指南，并且都得到了厚生劳动省的资助。
大多数组织都调查了全国范围内临床实践指南的传播和采用情况。在临床实践中的采用率估计在 70%以上。但是，预算较小的组织报告说调查时间约为 60%，而预算较大的组织报告说他们的指南调查成功率约为 100%。各组织的会长都认为有必要设立一个由国家政府直接运作的新组织。
在日本，要制定癌症相关的临床实践指南，有必要进行临床验证研究。项目必须有充足的资金支持，以维持和修订指南。此外，在建立任何登记系统之前，应解决法律和伦理问题。
