Alper M M, Garner P R, Spence J E, Quarrington A M
Obstet Gynecol. 1986 Jul;68(1):6-9.
Hysterosalpingography can be accomplished with either oil or water-soluble contrast medium. This randomized prospective study compared pregnancy rates in women who had hysterosalpingography with either water- or oil-soluble contrast material and were followed for six months. Fifteen of 60 (25%) patients who received water-soluble dye conceived compared with 14 of 46 (30%) patients in the oil-soluble group, a statistically insignificant difference. Furthermore, no difference in pregnancy rates within each subgroup of fertility diagnosis was detected. Intravasation was more common in patients administered oil-based contrast materials (six of 46 versus one of 60 patients, P = .02), although no serious consequences occurred. No difference in the amount of pain as assessed by pain scoring was experienced by patients in each group. The authors conclude that pregnancy rates are similar after hysterosalpingography with oil- and water-soluble contrast material, during at least the first six months after the procedure.
子宫输卵管造影可以使用油性或水溶性造影剂来完成。这项随机前瞻性研究比较了接受子宫输卵管造影时使用水溶性或油性造影剂且随访6个月的女性的妊娠率。接受水溶性染料的60名患者中有15名（25%）怀孕，而油性造影剂组的46名患者中有14名（30%）怀孕，差异无统计学意义。此外，在每个生育诊断亚组中均未检测到妊娠率的差异。油性造影剂给药患者的血管内造影剂外渗更常见（46名患者中有6名，而60名患者中有1名，P = 0.02），尽管未发生严重后果。通过疼痛评分评估，每组患者经历的疼痛程度没有差异。作者得出结论，在子宫输卵管造影术后至少头六个月内，使用油性和水溶性造影剂后的妊娠率相似。
