Psillas George, Antoniades Elias, Ieridou Fotini, Constantinidis Jannis
1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.
1st Academic Neurosurgery Department, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.
J Paediatr Child Health. 2019 Mar;55(3):299-304. doi: 10.1111/jpc.14190. Epub 2018 Aug 24.
To report the causes and clinical evaluation of children with facial nerve palsy (FNP) admitted to an affiliated university hospital during a 5-year period (2011-2015).
A total of 124 children were retrospectively categorised into two groups: idiopathic Bell's palsy (109 patients) and the second group into other FNP aetiologies (15 patients). All children received a standardised work-up and follow-up. Therapy consisted of steroid administration associated with antiviral treatment when a viral infection was suspected.
All children of the first group had a full recovery under oral steroids within 2 months of treatment. From the second group, seven children (46%) had a viral infection based on serological findings, two of them were positive for neurotropic herpes viruses, and one had Ramsay Hunt syndrome; six children with infectious FNP had recurrent FNP on the ipsilateral or contralateral side. Five patients had FNP as a complication of acute otitis media; three of them (60%) had partial or full recovery postoperatively. One child developed FNP following temporal bone trauma that had an uneventful recovery with conservative treatment. One child suffered from Melkersson-Rosenthal syndrome, and another child presented with FNP associated with unilateral hemiparesis following an ischaemic cerebral infarct.
Facial palsy in children is a manifestation of a heterogeneous group of causes. The most common aetiology of FNP in children in our study was idiopathic (Bell's palsy), followed by infective causes, such as acute otitis media and neurotropic herpes viruses. Therefore, treatment should be adapted to each patient depending on the underlying disease and severity of FNP.
报告一所附属大学医院在5年期间(2011 - 2015年)收治的面神经麻痹(FNP)患儿的病因及临床评估情况。
124名儿童被回顾性地分为两组:特发性贝尔麻痹(109例患者)和另一组为其他FNP病因(15例患者)。所有儿童均接受标准化检查和随访。治疗包括在怀疑有病毒感染时给予类固醇药物并联合抗病毒治疗。
第一组所有儿童在口服类固醇治疗后2个月内完全康复。第二组中,根据血清学检查结果,7名儿童(46%)有病毒感染,其中2名嗜神经性疱疹病毒呈阳性,1名患有拉姆齐·亨特综合征;6名感染性FNP儿童在同侧或对侧出现复发性FNP。5例患者的FNP是急性中耳炎的并发症,其中3例(60%)术后部分或完全康复。1名儿童因颞骨外伤发生FNP,经保守治疗后顺利康复。1名儿童患有梅尔克森 - 罗森塔尔综合征,另1名儿童在缺血性脑梗死出现与单侧偏瘫相关的FNP。
儿童面神经麻痹是多种病因的表现。本研究中儿童FNP最常见的病因是特发性(贝尔麻痹),其次是感染性病因,如急性中耳炎和嗜神经性疱疹病毒。因此,应根据潜在疾病和FNP的严重程度对每位患者进行个体化治疗。