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α受体阻滞剂(酚苄明)在早泄治疗中的作用。

Effect of an alpha-blocking agent (phenoxybenzamine) in the management of premature ejaculation.

作者信息

Beretta G, Chelo E, Fanciullacci F, Zanollo A

出版信息

Acta Eur Fertil. 1986 Jan-Feb;17(1):43-5.

PMID:3014791
Abstract

Phenoxybenzamine has been extremely effective in treating patients with vesical dysfunctions, its minimal side effects include anejaculation and delay and difficulty in ejaculation. Fifteen men were treated with phenoxybenzamine (PBZ) for premature ejaculation. Eight patients reported a subjective improvement of the time from penetration to ejaculation. PBZ is a well tolerated drug. The only side effect of the treatment was dry ejaculation. The Authors suggest its use in selected patients.

摘要

酚苄明在治疗膀胱功能障碍患者方面极为有效,其最小副作用包括射精障碍和射精延迟及困难。15名男性用酚苄明(PBZ)治疗早泄。8名患者报告从插入到射精的时间有主观改善。酚苄明是一种耐受性良好的药物。治疗的唯一副作用是干性射精。作者建议在特定患者中使用该药。

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Effect of an alpha-blocking agent (phenoxybenzamine) in the management of premature ejaculation.α受体阻滞剂(酚苄明)在早泄治疗中的作用。
Acta Eur Fertil. 1986 Jan-Feb;17(1):43-5.
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[Treatment of premature ejaculation with an alpha-blocker (phenoxybenzamine)].
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[Clinical study of sildenafil in the treatment of premature ejaculation complicated by erectile dysfunction].西地那非治疗合并勃起功能障碍的早泄的临床研究
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PSD502 improves ejaculatory latency, control and sexual satisfaction when applied topically 5 min before intercourse in men with premature ejaculation: results of a phase III, multicentre, double-blind, placebo-controlled study.对于早泄男性,在性交前5分钟局部应用PSD502可改善射精潜伏期、控制能力和性满意度:一项III期、多中心、双盲、安慰剂对照研究的结果。
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引用本文的文献

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The drug treatment of premature ejaculation.早泄的药物治疗。
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Premature ejaculation: do we have effective therapy?早泄:我们有有效的治疗方法吗?
Transl Androl Urol. 2013 Mar;2(1):45-53. doi: 10.3978/j.issn.2223-4683.2013.01.02.
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Impact of alpha blockers, 5-alpha reductase inhibitors and combination therapy on sexual function.α受体阻滞剂、5-α还原酶抑制剂及联合治疗对性功能的影响。
Curr Urol Rep. 2014 Oct;15(10):441. doi: 10.1007/s11934-014-0441-2.
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Medical therapy for premature ejaculation.早泄的医学治疗。
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In vitro measurement of ejaculation latency time (ELT) and the effects of vardenafil on ELT on lifelong premature ejaculators: placebo-controlled, double-blind, cross-over laboratory setting.在体外测量射精潜伏期 (ELT) 和伐地那非对终身早泄患者 ELT 的影响:安慰剂对照、双盲、交叉实验室设置。
Int Urol Nephrol. 2010 Dec;42(4):881-7. doi: 10.1007/s11255-010-9710-2. Epub 2010 Feb 20.
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Premature ejaculation: definition and drug treatment.早泄:定义与药物治疗
Drugs. 2007;67(4):547-68. doi: 10.2165/00003495-200767040-00005.
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Managing early ejaculation: what does the future hold?早泄的治疗:未来会怎样?
Rev Urol. 2004 Winter;6(1):5-10.
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Terazosin in the treatment of premature ejaculation: a short-term follow-up.
Int Urol Nephrol. 2005;37(4):773-7. doi: 10.1007/s11255-005-3616-4.
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Disorders of ejaculation.射精障碍
J Endocrinol Invest. 2002 Dec;25(11):1006-19. doi: 10.1007/BF03344077.