Kedia K R, Persky L
Urology. 1981 Dec;18(6):620-1. doi: 10.1016/0090-4295(81)90474-x.
Phenoxybenzamine (Dibenzyline) has been extremely effective in treating patients with detrusor dyssynergia. Its minimal side effects include: mouth dryness, nasal congestion, drowsiness and fatigue, nausea and vomiting, palpitations, ejaculatory failure, and retrograde ejaculation. Nineteen men treated with phenoxybenzamine for detrusor dyssynergia reported ejaculatory failure during treatment; normal ejaculation returned after treatment was discontinued. Postmasturbation urine and semen samples were analyzed for sperm and fructose. The results of the study suggest that ejaculatory failure was due to the lack of seminal emission into the posterior urethra, rather than retrograde ejaculation. Some implications of this study are also discussed.
酚苄明（双苄胺）在治疗逼尿肌协同失调患者方面极为有效。其轻微副作用包括：口干、鼻塞、嗜睡和疲劳、恶心和呕吐、心悸、射精失败以及逆行射精。19名接受酚苄明治疗逼尿肌协同失调的男性在治疗期间报告出现射精失败；治疗停止后射精恢复正常。对自慰后的尿液和精液样本进行了精子和果糖分析。研究结果表明，射精失败是由于缺乏精液排入后尿道，而非逆行射精。本文还讨论了该研究的一些意义。
